Beekman A T F, Spijker J
Tijdschr Psychiatr. 2018;60(3):156-160.
It is often said that a patient with depression can derive considerable benefit from personalised diagnostics and treatment.
AIM: To find out whether we have enough data to demonstrate that personalised diagnostics and personalised treatment of depression are better than what we do now and, if so, what specific action we should take.
METHOD: We review the literature on the foregoing topic.
RESULTS: There is ample evidence to support the view that the efficacy of treatment may improve quite dramatically if we are able to diagnose with much greater precision and select a treatment that is best suited to an individual person. Although there is less empirical evidence available with regard to a system that makes use of short regular feedback of unique personal data of patients and of the personal input of the professionals involved, these factors may nevertheless improve efficacy still further.
CONCLUSION: Although no hard evidence is available so far, for instance as a result of trials, there is sufficient evidence to support the further development of personalised diagnostics and personalised treatment of depression.
人们常说,抑郁症患者能从个性化诊断和治疗中获得显著益处。
查明我们是否有足够的数据来证明抑郁症的个性化诊断和个性化治疗比我们目前的做法更好,如果是这样,我们应该采取哪些具体行动。
我们回顾了关于上述主题的文献。
有充分的证据支持这样的观点,即如果我们能够更精确地进行诊断并选择最适合个体的治疗方法,治疗效果可能会大幅提高。尽管关于利用患者独特个人数据的定期简短反馈以及相关专业人员的个人投入的系统的实证证据较少,但这些因素仍可能进一步提高疗效。
尽管目前尚无确凿证据,例如来自试验的证据,但有足够的证据支持进一步开展抑郁症的个性化诊断和个性化治疗。