DeValentine S, Fredenburg M, Loretz L
Clin Podiatr Med Surg. 1987 Apr;4(2):395-412.
Diabetic foot infections are frequently much worse than the initial clinical appearance would indicate. Altered immune response, peripheral vascular disease, and neuropathy are key factors in the production of infection. Treatment must be based upon careful bacteriologic analysis and individualized antibiotic therapy. Surgical debridement, when indicated, is the mainstay of treatment. Partial foot amputation and salvage are always preferred over higher amputation when possible.
糖尿病足感染往往比最初的临床表现更为严重。免疫反应改变、外周血管疾病和神经病变是引发感染的关键因素。治疗必须基于细致的细菌学分析和个体化的抗生素治疗。如有指征，手术清创是治疗的主要手段。在可能的情况下，足部部分截肢和保肢总是优于高位截肢。
