Department of Integrated Genetics, National Institute of Genetics, Yata 1111, Shizuoka 411-8540, Japan.
Department of Integrated Genetics, National Institute of Genetics, Yata 1111, Shizuoka 411-8540, Japan; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
Curr Opin Genet Dev. 2018 Apr;49:43-48. doi: 10.1016/j.gde.2018.02.012. Epub 2018 Mar 8.
Although transposable elements (TEs) have been regarded as genomic parasites, accumulating evidence suggests that they can also have beneficial roles in evolution of diverse biological processes. In this review, we focus on epigenetic control of TEs as sources of selectable phenotypic variation, with an emphasis on their connections to defense responses.
尽管转座元件(TEs)一直被视为基因组寄生虫,但越来越多的证据表明,它们在多种生物过程的进化中也可以发挥有益的作用。在这篇综述中,我们重点关注转座元件的表观遗传控制作为可选择表型变异的来源,特别强调它们与防御反应的联系。