Geyl S, Jacques J, Parreau S, Cypierre A, Tabouret T, Gondran G, Ly K H, Liozon E, Lapébie F X, Bezanahary H, Palat S, Monteil J, Loustaud-Ratti V, Fauchais A L
Service d'hépato-gastro-entérologie, CHU Limoges, 87000 Limoges, France.
Service d'hépato-gastro-entérologie, CHU Limoges, 87000 Limoges, France.
Rev Med Interne. 2018 Jun;39(6):427-430. doi: 10.1016/j.revmed.2018.02.007. Epub 2018 Mar 8.
Upper digestive symptoms may be present in up to 50% of patients with primary Sjögren syndrome (pSS). We report a retrospective cohort of gastroparesis in a population of pSS presenting unexplained dyspepsia. Delayed gastric emptying was defined by a gastric emptying time above 113min or by a retention percentage at 4h more than 10% on scintigraphy.
Eleven patients with primary Sjögren syndrome and gastroparesis were included in a retrospective study. Every patients were women of age 48±18y. The average time of gastric emptying was 725,18±704,45min. 64% of patients had abdominal pain or gastric heaviness. A central or peripheral neurologic involvement was described in respectively 9 and 27% of cases. The diagnostic delay of gastroparesis was higher than 24 months.
In primary Sjögren syndrome, gastroparesis should be suspected in case of unexplained dyspepsia, and a scintigraphy performed to prove the diagnosis. A neurologic involvement could explain gastroparesis, but prospective studies are needed for a better understanding of this disorder.
高达50%的原发性干燥综合征（pSS）患者可能出现上消化道症状。我们报告了一组pSS患者中胃轻瘫的回顾性队列研究，这些患者表现为无法解释的消化不良。胃排空延迟通过胃排空时间超过113分钟或闪烁扫描4小时时潴留百分比超过10%来定义。
11例原发性干燥综合征合并胃轻瘫患者纳入回顾性研究。所有患者均为女性，年龄48±18岁。平均胃排空时间为725.18±704.45分钟。64%的患者有腹痛或胃部沉重感。分别有9%和27%的病例存在中枢或周围神经受累。胃轻瘫的诊断延迟超过24个月。
在原发性干燥综合征中，出现无法解释的消化不良时应怀疑胃轻瘫，并进行闪烁扫描以证实诊断。神经受累可能解释胃轻瘫，但需要前瞻性研究以更好地理解这种疾病。
