1 Division of Dermatology, Université de Montréal, Montréal, QC, Canada.
2 Division of Pathology, Université de Montréal, Montréal, QC, Canada.
J Cutan Med Surg. 2018 Sep/Oct;22(5):527-529. doi: 10.1177/1203475418763540. Epub 2018 Mar 11.
The diagnosis of exaggerated bite reactions is based on the clinical and pathological characteristics of the lesions. These reactions can be an indicator of impending immune suppression.
The authors report the case of a 35-year-old pregnant woman who presented with a pruriginous vesicular and pustular eruption over her thighs and buttocks. The clinical and pathological findings were compatible with an exaggerated bite reaction. The patient did not report any severe or exaggerated reaction to insect bites in the past. It was her first episode.
Exaggerated bite reactions have been described with hematological malignancies, mostly chronic lymphocytic leukemia. In our literature review, we did not find any reports of severe local bite reactions occurring during pregnancy. We hypothesize that the changes in the immune system during pregnancy might explain the development of exaggerated bite reactions in our patient.
夸张型虫咬反应的诊断基于病变的临床和病理特征。这些反应可能是即将发生免疫抑制的指标。
作者报告了一例 35 岁孕妇的病例，其大腿和臀部出现瘙痒性水疱和脓疱疹。临床和病理发现与夸张型虫咬反应相符。患者过去没有报告任何严重或夸张的昆虫叮咬反应。这是她第一次发作。
夸张型虫咬反应已在血液系统恶性肿瘤中被描述，主要是慢性淋巴细胞白血病。在我们的文献复习中，我们没有发现任何关于怀孕期间严重局部虫咬反应的报告。我们假设怀孕期间免疫系统的变化可能解释了我们患者中夸张型虫咬反应的发生。
