Lee Ming-Huei, Chang Kun-Min, Tsai Wen-Chen
Department of Urology, Taichung Hospital, Ministry of Health and Welfare, No. 199, sec. 1, San-Min Road, Taichung, 40343, Taiwan, Republic of China.
Department of Urology, Feng Yuan Hospital, Ministry of Health and Welfare, Taichung, Taiwan, Republic of China.
Int Urogynecol J. 2018 Jul;29(7):1045-1050. doi: 10.1007/s00192-018-3574-x. Epub 2018 Mar 12.
The objective was to calculate the morbidity rate and medical utilization of interstitial cystitis/painful bladder syndrome (IC/PBS) over 12 years using a nationwide database of Taiwan.
This was a cohort study of the Longitudinal Health Insurance Database 2010 with new diagnoses of IC/PBS from 2002 through 2013. The morbidity rate was adjusted for age, sex, and calendar date using density methods. Moreover, medical utilization during the study period was measured.
It was observed that the incidence of IC/PBS was 21.8/100,000 in 2002 and 21.1/100,000 in 2013. The prevalence of IC/PBS was 21.8/100,000 in 2002 and 40.2/100,000 in 2013. In 2003, the incidence and prevalence of women was 28.6/100,000 and 63.5/100,000 respectively. The incidence and prevalence of men was 12.3/100,000 and 19.4/100,000 respectively. In 2002, the incidence was 45.5/100,000, 32.4/100,000, and 9/100,000 in the age groups above 65, 40-65, and under 40 years respectively. The prevalence in 2003 was 86.3/100,000, 63.1/100,000, and 16.4/100,000 in age groups above 65, 40-65, and under 40 years respectively. This pattern was similar until 2013. The mean outpatient and inpatient visit time was 4.8 and 1.8 times per year respectively. The mean surgical fee (US$ 246.6 ± 304.5) was 23.6% of the total fee.
The morbidity rate of IC/PBS showed a higher incidence and prevalence in women and older patients. A new drug for the treatment of IC/PBS may be a factor of the peak in the morbidity rate. The increase in medical utilization could be explained by the awareness of physicians and patients seeking medical help.
目的是利用台湾的全国性数据库计算12年间间质性膀胱炎/膀胱疼痛综合征（IC/PBS）的发病率和医疗利用率。
这是一项对2010年纵向健康保险数据库的队列研究，纳入了2002年至2013年新诊断为IC/PBS的患者。使用密度法对发病率进行年龄、性别和日历日期调整。此外，还对研究期间的医疗利用率进行了测量。
观察到2002年IC/PBS的发病率为21.8/10万，2013年为21.1/10万。2002年IC/PBS的患病率为21.8/10万，2013年为40.2/10万。2003年，女性的发病率和患病率分别为28.6/10万和63.5/10万。男性的发病率和患病率分别为12.3/10万和19.4/10万。2002年，65岁以上、40 - 65岁和40岁以下年龄组的发病率分别为45.5/10万、32.4/10万和9/10万。2003年，65岁以上、40 - 65岁和40岁以下年龄组的患病率分别为86.3/10万、63.1/10万和16.4/10万。直到2013年这种模式都相似。平均门诊和住院就诊次数分别为每年4.8次和1.8次。平均手术费用（246.6美元±304.5美元）占总费用的23.6%。
IC/PBS的发病率在女性和老年患者中显示出较高的发生率和患病率。一种治疗IC/PBS的新药可能是发病率峰值的一个因素。医疗利用率的增加可以通过医生和患者寻求医疗帮助的意识来解释。
