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巴西东南部圣保罗州的17个Y染色体短串联重复序列单倍型多样性

17 Y-STR haplotype diversity in São Paulo state (southeast of Brazil).

作者信息

de Souza Leandro Fonseca, da Motta Carlos Henrique Ares Silveira, Moura-Neto Rodrigo Soares

机构信息

Centro de Energia Nuclear na Agricultura, Piracicaba, São Paulo, Brazil.

Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Santo André, São Paulo, Brazil.

出版信息

Int J Legal Med. 2019 Jan;133(1):81-83. doi: 10.1007/s00414-018-1823-7. Epub 2018 Mar 12.

Abstract

A sample of 158 Brazilian males from São Paulo (SP), Brazilian southeast, was typed for 17 Y-STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, YGATA_H4.1, and DYS385ab). A total of 158 haplotypes were identified, of which all were unique. The haplotype diversity and discrimination capacity were calculated in 1.0 and the genetic diversity was 67.4%. Pairwise haplotype distances showed that the São Paulo population is not significantly different from Rio de Janeiro and Portugal, but is different from African and Native American.

摘要

对来自巴西东南部圣保罗(SP)的158名巴西男性样本进行了17个Y染色体短串联重复序列(Y-STR)基因座(DYS19、DYS389I、DYS389II、DYS390、DYS391、DYS392、DYS393、DYS437、DYS438、DYS439、DYS448、DYS456、DYS458、DYS635、YGATA_H4.1和DYS385ab)的分型。共鉴定出158种单倍型,所有单倍型均为独特型。单倍型多样性和鉴别能力计算值为1.0,基因多样性为67.4%。成对单倍型距离显示,圣保罗人群与里约热内卢和葡萄牙人群无显著差异,但与非洲和美洲原住民人群不同。

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