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基层医疗中急性呼吸道感染(ARTI)的抗生素使用;哪些因素影响处方开具,为何其很重要?一项叙述性综述。

Antibiotic use for acute respiratory tract infections (ARTI) in primary care; what factors affect prescribing and why is it important? A narrative review.

作者信息

O'Connor Ray, O'Doherty Jane, O'Regan Andrew, Dunne Colum

机构信息

Graduate Entry Medical School, University of Limerick, Limerick City, Limerick, 000, Ireland.

出版信息

Ir J Med Sci. 2018 Nov;187(4):969-986. doi: 10.1007/s11845-018-1774-5. Epub 2018 Mar 12.

Abstract

BACKGROUND

Antimicrobial resistance is an emerging global threat to health and is associated with increased consumption of antibiotics. Seventy-four per cent of antibiotic prescribing takes place in primary care. Much of this is for inappropriate treatment of acute respiratory tract infections.

AIMS

To review the published literature pertaining to antibiotic prescribing in order to identify and understand the factors that affect primary care providers' prescribing decisions.

METHODS

Six online databases were searched for relevant paper using agreed criteria. One hundred ninety-five papers were retrieved, and 139 were included in this review.

RESULTS

Primary care providers are highly influenced to prescribe by patient expectation for antibiotics, clinical uncertainty and workload induced time pressures. Strategies proven to reduce such inappropriate prescribing include appropriately aimed multifaceted educational interventions for primary care providers, mass media educational campaigns aimed at healthcare professionals and the public, use of good communication skills in the consultation, use of delayed prescriptions especially when accompanied by written information, point of care testing and, probably, longer less pressurised consultations. Delayed prescriptions also facilitate focused personalised patient education.

CONCLUSION

There is an emerging consensus in the literature regarding strategies proven to reduce antibiotic consumption for acute respiratory tract infections. The widespread adoption of these strategies in primary care is imperative.

摘要

背景

抗菌药物耐药性是一个新出现的全球健康威胁,且与抗生素使用量增加相关。74%的抗生素处方开具发生在初级医疗保健中。其中大部分是用于对急性呼吸道感染的不恰当治疗。

目的

回顾已发表的有关抗生素处方开具的文献,以识别并理解影响初级医疗保健提供者处方决策的因素。

方法

按照商定的标准在六个在线数据库中检索相关论文。检索到195篇论文,本综述纳入了139篇。

结果

患者对抗生素的期望、临床不确定性以及工作量导致的时间压力对初级医疗保健提供者的处方开具影响很大。已证实可减少此类不恰当处方开具的策略包括针对初级医疗保健提供者进行有针对性的多方面教育干预、针对医疗保健专业人员和公众开展的大众媒体教育活动、在诊疗过程中运用良好的沟通技巧、使用延迟处方(尤其是在伴有书面信息时)、即时检测,以及可能进行时间压力较小的更长时间的诊疗。延迟处方还便于开展有针对性的个性化患者教育。

结论

关于已证实可减少急性呼吸道感染抗生素使用量的策略,文献中已逐渐形成共识。在初级医疗保健中广泛采用这些策略势在必行。

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