Department of Therapy Services, University of Chicago Medicine, Chicago, IL, USA.
Department of Pediatrics, Section of Neonatology, Comer Children's Hospital, University of Chicago, Chicago, IL, USA.
Dev Med Child Neurol. 2018 Dec;60(12):1239-1243. doi: 10.1111/dmcn.13736. Epub 2018 Mar 13.
To determine the relationship between the Test of Infant Motor Performance (TIMP) at 3 months and cognitive, language, and motor outcomes on the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) at 2 years of age in high-risk infants born preterm.
One hundred and six infants (47 females, 59 males) born at earlier than 31 weeks gestational age were prospectively tested with the TIMP at 10 to 15 weeks after term age and were assessed again with the Bayley-III at 2 years corrected age. Sensitivity and specificity were calculated for various cut points of the TIMP z-score and Bayley-III composite scores of no more than 85.
The TIMP z-scores at 10 to 15 weeks of age were significantly associated with all three subscales on the Bayley-III at 2 years of age (p<0.001). Using a TIMP z-score cutoff of -0.5, specificity was relatively high for cognitive (87%), language (88%), and motor (89%) outcomes, but sensitivity was low (cognitive 41%, language 49%, motor 57%).
This study demonstrates that the TIMP is related to cognitive, language, and motor outcomes on the Bayley-III at 2 years of age in high-risk infants born preterm.
The Test of Infant Motor Performance (TIMP) predicts Bayley Scales of Infant and Toddler Development, Third Edition outcomes at 2 years of age. The TIMP is relatively good at discriminating between children who will and will not have typical development.
确定早产儿高危儿在 3 个月时进行婴儿运动表现测试(TIMP)与在 2 岁时进行贝利婴幼儿发育量表第三版(Bayley-III)的认知、语言和运动结果之间的关系。
106 名婴儿(47 名女性,59 名男性)于妊娠 31 周前早产,于矫正胎龄 10 至 15 周时行 TIMP 测试,2 岁时再次行 Bayley-III 测试。计算 TIMP z 评分和 Bayley-III 综合评分不超过 85 的各种切点的灵敏度和特异性。
矫正胎龄 10 至 15 周时的 TIMP z 评分与 2 岁时 Bayley-III 的三个分量表均显著相关(p<0.001)。使用 TIMP z 评分截断值-0.5,认知(87%)、语言(88%)和运动(89%)结局的特异性相对较高,但敏感性较低(认知 41%,语言 49%,运动 57%)。
本研究表明,早产儿高危儿的 TIMP 与 2 岁时 Bayley-III 的认知、语言和运动结局相关。
婴儿运动表现测试(TIMP)可预测 2 岁时贝利婴幼儿发育量表第三版的结果。TIMP 在区分具有典型和非典型发育的儿童方面表现良好。