从 3D 类器官回到 2D 类肠。
From 3D Organoids back to 2D Enteroids.
机构信息
Koch Institute for Integrative Cancer Research at MIT and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.
Koch Institute for Integrative Cancer Research at MIT and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
出版信息
Dev Cell. 2018 Mar 12;44(5):533-534. doi: 10.1016/j.devcel.2018.02.016.
In this issue of Developmental Cell, Thorne et al. (2018) describe a simple, scalable method to culture 2D enteroid monolayers that surprisingly recapitulates many of the features of 3D organoid cultures and in vivo intestinal tissue and can be used for high-throughput microscopy-based experiments.
本期《发育细胞》中，Thorne 等人（2018）描述了一种简单、可扩展的方法来培养 2D 类器官单层，令人惊讶的是，它再现了许多 3D 类器官培养和体内肠道组织的特征，并且可以用于基于高通量显微镜的实验。
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