Chao Calvin, Vanguri Vijay, Uy Karl
Division of Thoracic Surgery, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
Department of Pathology, UMass Memorial Medical Center, University of Massachusetts Medical School, Worcester, MA, USA.
Case Rep Pulmonol. 2018 Feb 4;2018:1424275. doi: 10.1155/2018/1424275. eCollection 2018.
First described in 2005, the Mullerian derived cyst in the mediastinum is a rare finding with few subsequent reports. We report a case of Mullerian cyst occurring in the mediastinum of a 49-year-old female that was resected by robot-assisted thoracoscopic surgery. To our knowledge, this is the first report of robot-assisted resection of Hattori's cyst. Histopathologic analysis revealed ciliated Mullerian-type tubal epithelium positive for paired box gene 8 (PAX8), estrogen receptor (ER), and progesterone receptor (PR), confirming Mullerian differentiation. We also review the clinical presentation, pathology, and differential diagnosis of such cysts.
纵隔苗勒管源性囊肿于2005年首次被描述，是一种罕见的发现，后续报道较少。我们报告一例49岁女性纵隔内发生的苗勒管囊肿，该囊肿通过机器人辅助胸腔镜手术切除。据我们所知，这是首例机器人辅助切除Hattori囊肿的报告。组织病理学分析显示，囊肿内衬有纤毛的苗勒管型输卵管上皮，配对盒基因8（PAX8）、雌激素受体（ER）和孕激素受体（PR）呈阳性，证实为苗勒管分化。我们还对这类囊肿的临床表现、病理及鉴别诊断进行了综述。
