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憩室病的择期手术与早期择期手术:非急诊治疗最佳时机的回顾性研究

Elective vs. early elective surgery in diverticular disease: a retrospective study on the optimal timing of non-emergency treatment.

作者信息

Warwas Felix Benjamin, Schneider Berthold

机构信息

Department of Oral and Maxillofacial Surgery, University Hospital Bonn, Siegmund-Freud-Straße 25, 53127, Bonn, Northrhine-Westphalia, Germany.

Department of General and Visceral Surgery, St. Marienhospital Bonn, Robert-Koch-Straße 1, 53115, Bonn, Northrhine-Westphalia, Germany.

出版信息

Int J Colorectal Dis. 2018 May;33(5):531-539. doi: 10.1007/s00384-018-3022-x. Epub 2018 Mar 13.

DOI:10.1007/s00384-018-3022-x
PMID:29536239
Abstract

PURPOSE

This study set out to compare the in-hospital outcomes of early elective and elective laparoscopic sigmoidectomy due to diverticulitis.

METHODS

We examined the data for 378 diverticulitis patients who received an elective laparoscopic sigmoid resection between 2008 and 2012. We divided the patients into two groups: elective (group A, n = 278) and early elective (group B, n = 100). Patients in group A received surgery during the inflammation-free interval, and those in group B immediately after treating the attack with IV antibiotics for a mean period of 8 days (IQR = 3).

RESULTS

Overall mortality was 0%. The mean operation duration was the same in both groups being 77.5 and 80 min respectively. There was no significant difference in the outcomes between the two groups, measured using the Clavien-Dindo classification of surgical complication (CCSC; p = 0.992). A revision due to complications was necessary in 16 cases (group A) and six cases (group B) (p = 0.820). The conversion rate to open surgery was low (six individuals in group A, vs. four in group B; p = 0.331). Patients in group B suffered significantly fewer diverticulitis attacks (three in group A, vs. two in group B; p = 0.026).

CONCLUSION

Our study showed no difference in outcome between elective and early elective cases. Operation durations were optimal in both cases and were 50% shorter than those recorded in the literature. An early elective operation represents a good treatment option, especially for patients suffering from complicated diverticulitis.

摘要

目的

本研究旨在比较因憩室炎行早期择期和择期腹腔镜乙状结肠切除术的院内结局。

方法

我们检查了2008年至2012年间接受择期腹腔镜乙状结肠切除术的378例憩室炎患者的数据。我们将患者分为两组:择期手术组(A组,n = 278)和早期择期手术组(B组,n = 100)。A组患者在炎症消退期接受手术,B组患者在用静脉抗生素平均治疗8天(四分位间距 = 3天)的发作期后立即接受手术。

结果

总死亡率为0%。两组的平均手术时间相同,分别为77.5分钟和80分钟。使用Clavien-Dindo手术并发症分类(CCSC)测量,两组的结局无显著差异(p = 0.992)。A组有16例(B组有6例)因并发症需要进行再次手术(p = 0.820)。转为开放手术的发生率较低(A组6例,B组4例;p = 0.331)。B组患者的憩室炎发作明显较少(A组3例,B组2例;p = 0.026)。

结论

我们的研究表明,择期和早期择期病例的结局没有差异。两种情况下的手术时间均最佳,比文献报道的时间短50%。早期择期手术是一种很好的治疗选择,特别是对于患有复杂性憩室炎的患者。

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Elective vs. early elective surgery in diverticular disease: a retrospective study on the optimal timing of non-emergency treatment.憩室病的择期手术与早期择期手术:非急诊治疗最佳时机的回顾性研究
Int J Colorectal Dis. 2018 May;33(5):531-539. doi: 10.1007/s00384-018-3022-x. Epub 2018 Mar 13.
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[The current view of surgical treatment of diverticular disease].[憩室病的外科治疗现状]
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Laparoscopic sigmoid colectomy for complicated diverticulitis is safe: review of 576 consecutive colectomies.腹腔镜乙状结肠切除术治疗复杂性憩室炎是安全的:对576例连续结肠切除术的回顾
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引用本文的文献

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Langenbecks Arch Surg. 2022 Dec;407(8):3259-3274. doi: 10.1007/s00423-022-02698-z. Epub 2022 Oct 10.
2
Early elective versus elective sigmoid resection in diverticular disease: not only timing matters-a single institutional retrospective review of 133 patients.早期择期与择期乙状结肠切除术治疗憩室病:不仅时机重要——单中心回顾性分析 133 例患者。
Langenbecks Arch Surg. 2022 Jun;407(4):1613-1623. doi: 10.1007/s00423-022-02464-1. Epub 2022 Feb 22.

本文引用的文献

1
Laparoscopic sigmoid colectomy for complicated diverticulitis is safe: review of 576 consecutive colectomies.腹腔镜乙状结肠切除术治疗复杂性憩室炎是安全的:对576例连续结肠切除术的回顾
Surg Endosc. 2016 Apr;30(4):1629-34. doi: 10.1007/s00464-015-4393-5. Epub 2015 Aug 15.
2
Sigmoid stricture associated with diverticular disease should be an indication for elective surgery with lymph node clearance.与憩室病相关的乙状结肠狭窄应是进行选择性手术并清扫淋巴结的指征。
J Visc Surg. 2015 Sep;152(4):211-5. doi: 10.1016/j.jviscsurg.2015.04.001. Epub 2015 May 6.
3
Modern concepts in diverticular disease.
憩室病的现代概念
J Clin Gastroenterol. 2015 May-Jun;49(5):358-69. doi: 10.1097/MCG.0000000000000308.
4
Complications of diverticular disease: surgical laparoscopic treatment.憩室病的并发症:腹腔镜手术治疗
G Chir. 2014 May-Jun;35(5-6):126-8.
5
[Surgical Indications for Diverticulitis in Germany: Are All Operations Justified?].[德国憩室炎的手术指征:所有手术都合理吗?]
Zentralbl Chir. 2015 Dec;140(6):585-90. doi: 10.1055/s-0032-1328593. Epub 2013 Aug 1.
6
Elective resection for ongoing diverticular disease significantly improves quality of life.择期切除持续存在的憩室病可显著提高生活质量。
Dig Surg. 2013;30(3):190-7. doi: 10.1159/000346482. Epub 2013 Jul 6.
7
The evolving role of laparoscopy in colonic diverticular disease: a systematic review.腹腔镜在结肠憩室病中的作用演变:系统评价。
World J Surg. 2013 Mar;37(3):629-38. doi: 10.1007/s00268-012-1872-x.
8
Identifying important predictors for anastomotic leak after colon and rectal resection: prospective study on 616 patients.确定结直肠切除术后吻合口漏的重要预测因素:616 例患者的前瞻性研究。
Ann Surg. 2013 Jan;257(1):108-13. doi: 10.1097/SLA.0b013e318262a6cd.
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Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis.抗生素治疗急性单纯性憩室炎的随机临床试验。
Br J Surg. 2012 Apr;99(4):532-9. doi: 10.1002/bjs.8688. Epub 2012 Jan 30.
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Timing of rectosigmoid resection for diverticular disease: the patient's view.直肠乙状结肠切除术治疗憩室病的时机:患者的观点。
Colorectal Dis. 2012 Mar;14(3):e111-6. doi: 10.1111/j.1463-1318.2011.02801.x.