Rebora A
Dermatologica. 1987;174(5):214-8. doi: 10.1159/000249182.
To explain why in alopecia areata the hair falls out in a particular area the hypothesis is proposed that the area occurs as a stochastic event only in those subjects who, in a restricted zone of their scalp, happen to have a group of hairs that are simultaneously in the early anagen VI subphase of the hair cycle. Once this point has been accepted, a number of conclusions may be drawn. Especially important is the inference that only people with low percentages of telogen hairs are likely to exhibit areas, whereas those with androgenetic alopecia, when affected by alopecia areata, preferentially show a diffuse and delayed hair loss that has the features of Kligman's telogen effluvium (alopecia areata incognita). Epidemiological evidence is provided.
为了解释斑秃患者为何在特定区域脱发,提出了一种假说:该区域是一种随机事件,仅发生在那些头皮有限区域内恰好有一组毛发同时处于毛发生长周期的早生长期VI亚期的个体身上。一旦接受了这一点,就可以得出一些结论。特别重要的是这样一个推论,即只有休止期毛发比例低的人可能出现脱发区域,而雄激素性脱发患者在患斑秃时,更倾向于表现出具有克利格曼休止期脱发(隐匿性斑秃)特征的弥漫性和延迟性脱发。文中提供了流行病学证据。