一种用于蛋白质组学研究中敏感 HSA 磷光染色的新型铱（III）配合物。
A novel iridium(iii) complex for sensitive HSA phosphorescence staining in proteome research.
机构信息
College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, 518060, P. R. China.
出版信息
Chem Commun (Camb). 2018 Mar 27;54(26):3282-3285. doi: 10.1039/c8cc01597j.
PMID:29537015
Abstract
We report a novel organo-iridium(iii) complex (Ir1) for the selective and sensitive determination of human serum albumin (HSA). The phosphorescence of Ir1 is turned-on by HSA in the urinary system. Importantly, Ir1 is much simpler and less time-consuming for HSA staining than Coomassie blue in proteomics studies.
摘要
我们报告了一种新型的有机铱（III）配合物（Ir1），用于选择性和灵敏地测定人血清白蛋白（HSA）。Ir1 的磷光在泌尿系统中被 HSA 打开。重要的是，与蛋白质组学研究中的考马斯亮蓝相比，Ir1 用于 HSA 染色更简单、耗时更少。
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