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An epistaxis severity score for hereditary hemorrhagic telangiectasia.遗传性出血性毛细血管扩张症的鼻出血严重程度评分。
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International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia.国际遗传性出血性毛细血管扩张症诊断和管理指南。
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维生素D水平与遗传性出血性毛细血管扩张症的鼻出血严重程度及出血持续时间相关。

Vitamin D levels are associated with epistaxis severity and bleeding duration in hereditary hemorrhagic telangiectasia.

作者信息

Weber Lauren Marissa, McDonald Jamie, Whitehead Kevin

机构信息

University of Utah School of Medicine, Salt Lake City, UT 84132, USA.

Departments of Radiology and Pathology, Salt Lake City, UT 84132, USA.

出版信息

Biomark Med. 2018 Apr;12(4):365-371. doi: 10.2217/bmm-2017-0229. Epub 2018 Mar 14.

DOI:10.2217/bmm-2017-0229
PMID:29537299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6367804/
Abstract

AIM

To explore the association between vitamin D levels and mild versus severe epistaxis, as well as the overall epistaxis severity score (ESS) in patients with hereditary hemorrhagic telangiectasia.

PATIENTS & METHODS: A retrospective chart review of 198 patients was performed to explore the relationship between vitamin D levels and the ESS. Vitamin D levels were also compared with those with mild epistaxis to those with severe epistaxis.

RESULTS

A significant difference was found between patient's vitamin D levels and their associated ESS and duration of epistaxis. Patients with mild epistaxis had higher levels of vitamin D than patients with severe epistaxis.

CONCLUSION

Vitamin D is associated with features of hereditary hemorrhagic telangiectasia including ESS, bleeding time and epistaxis severity.

摘要

目的

探讨遗传性出血性毛细血管扩张症患者维生素D水平与轻度及重度鼻出血之间的关联,以及鼻出血总体严重程度评分(ESS)。

患者与方法

对198例患者进行回顾性病历审查,以探究维生素D水平与ESS之间的关系。还比较了轻度鼻出血患者与重度鼻出血患者的维生素D水平。

结果

发现患者的维生素D水平与其相关的ESS及鼻出血持续时间之间存在显著差异。轻度鼻出血患者的维生素D水平高于重度鼻出血患者。

结论

维生素D与遗传性出血性毛细血管扩张症的特征相关,包括ESS、出血时间和鼻出血严重程度。