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采用高度解耦的射频电路对用于放射治疗磁共振治疗计划的柔性 MRI 接收线圈阵列进行特性描述和评估。

Characterization and evaluation of a flexible MRI receive coil array for radiation therapy MR treatment planning using highly decoupled RF circuits.

机构信息

Department of Radiology, Mayo Clinic and Foundation, Rochester, MN, United States of America.

出版信息

Phys Med Biol. 2018 Apr 13;63(8):08NT02. doi: 10.1088/1361-6560/aab691.

DOI:10.1088/1361-6560/aab691
PMID:29537384
Abstract

The growth in the use of magnetic resonance imaging (MRI) data for radiation therapy (RT) treatment planning has been facilitated by scanner hardware and software advances that have enabled RT patients to be imaged in treatment position while providing morphologic and functional assessment of tumor volumes and surrounding normal tissues. Despite these advances, manufacturers have been slow to develop radiofrequency (RF) coils that closely follow the contour of a RT patient undergoing MR imaging. Instead, relatively large form surface coil arrays have been adapted from diagnostic imaging. These arrays can be challenging to place on, and in general do not conform to the patient's body habitus, resulting in sub optimal image quality. The purpose of this study is to report on the characterization of a new flexible and highly decoupled RF coil for use in MR imaging of RT patients. Coil performance was evaluated by performing signal-to-noise ratio (SNR) and noise correlation measurements using two coil (SNR) and four coil (noise correlation) element combinations as a function of coil overlap distance and comparing these values to those obtained using conventional coil elements. In vivo testing was performed in both normal volunteers and patients using a four and 16 element RF coil. Phantom experiments demonstrate the highly decoupled nature of the new coil elements when compared to conventional RF coils, while in vivo testing demonstrate that these coils can be integrated into extremely flexible and form fitting substrates that follow the exact contour of the patient. The new coil design addresses limitations imposed by traditional surface coil arrays and have the potential to significantly impact MR imaging for both diagnostic and RT applications.

摘要

磁共振成像(MRI)数据在放射治疗(RT)治疗计划中的使用不断增加,这得益于扫描仪硬件和软件的进步,使 RT 患者能够在治疗体位进行成像,同时对肿瘤体积和周围正常组织进行形态和功能评估。尽管取得了这些进展,但制造商开发与接受 MRI 的 RT 患者轮廓紧密贴合的射频(RF)线圈的速度仍然缓慢。相反,相对较大的形式表面线圈阵列已经从诊断成像中进行了改编。这些阵列在放置时具有挑战性,并且通常不符合患者的身体形态,导致图像质量不理想。本研究的目的是报告一种新的灵活且高度解耦的 RF 线圈,用于 RT 患者的 MRI 成像。通过使用两个线圈(SNR)和四个线圈(噪声相关)元件组合来执行信噪比(SNR)和噪声相关测量,评估线圈性能作为线圈重叠距离的函数,并将这些值与使用常规线圈元件获得的值进行比较。使用四元和十六元 RF 线圈在正常志愿者和患者中进行了体内测试。在与传统 RF 线圈进行比较时,体模实验证明了新线圈元件的高度解耦特性,而体内测试则证明了这些线圈可以集成到非常灵活且贴合患者精确轮廓的基底中。新的线圈设计解决了传统表面线圈阵列所带来的限制,并有可能对诊断和 RT 应用的 MRI 成像产生重大影响。

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