Popović Zoran B, Sato Kimi, Desai Milind Y
Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, USA.
Cardiovasc Diagn Ther. 2018 Feb;8(1):18-28. doi: 10.21037/cdt.2017.07.02.
Quantitation of diastolic function centers on the assessment of active and passive ventricular properties, and involves measurement estimates of ventricular relaxation, and chamber and myocardial stiffness. Diastolic dysfunction is a propensity to develop increased left ventricular (LV) end-diastolic pressure. Recently American Society of Echocardiography and European Association of Cardiovascular Imaging (ASE/EACVI) proposed a new grading system. While the new guidelines are ambiguous and with cutoff points that may misclassify patients as both sicker and healthier than they are. This article outlines the pathophysiology behind the diastolic dysfunction and role and limitation of echocardiographic assessment in predicting LV diastolic dysfunction.
舒张功能的定量主要集中在对心室主动和被动特性的评估上,包括对心室舒张、腔室和心肌僵硬度的测量估计。舒张功能障碍是左心室舒张末期压力升高的一种倾向。最近,美国超声心动图学会和欧洲心血管影像协会(ASE/EACVI)提出了一种新的分级系统。然而,新指南含糊不清,其临界点可能会将患者错误分类为比实际病情更严重或更健康的情况。本文概述了舒张功能障碍背后的病理生理学,以及超声心动图评估在预测左心室舒张功能障碍中的作用和局限性。