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亚致死剂量膳食汞对刺参生长性能、生物累积及抗氧化酶活性的影响

The Effects of Sub-lethal Dietary Mercury on Growth Performance, Bioaccumulation, and Activities of Antioxidant Enzymes in Sea Cucumber, Apostichopus japonicus.

作者信息

Li Zequn, Ren Tongjun, Han Yuzhe, Jiang Zhiqiang, Hu Yanan, Bai Zhuoan, Wang Lianshun, Ding Jingyun

机构信息

Key Laboratory of Mariculture & Stock Enhancement in North China's Sea, Ministry of Agriculture, Dalian Ocean University, Dalian, 116023, China.

出版信息

Bull Environ Contam Toxicol. 2018 May;100(5):683-689. doi: 10.1007/s00128-018-2321-9. Epub 2018 Mar 14.

DOI:10.1007/s00128-018-2321-9
PMID:29541817
Abstract

Triplicate groups of sea cucumbers (4.83 ± 0.15 g) were exposed to one of the four nominal concentrations of dietary mercury [0 (control), 67.6, 338, and 676 mg/kg dry weight, and actually total mercury were 17.55, 87.00, 275.50, 468.50 mg/kg, respectively; Table 3] for 21 days. Mercury accumulation in the intestine showed the greatest mercury burden (77.96 ± 1.20 mg Hg/kg tissue wet weight basis). However, survival rate (SR) was not affected. Body weight gain after the 676 mg Hg/kg treatment was significantly lower than the control group. The feed conversion rate of the 676 mg Hg/kg treatment group was significantly higher than the control group. Additionally, the superoxide dismutase (SOD) and total antioxidant capacity (T-AOC) of sea cucumbers decreased as the mercury dose increased. SOD, T-AOC and alkaline phosphatase of the 676 mg Hg/kg treatment group were significantly lower than the control group. However, there were no significant differences between the four groups in acid phosphatase and catalase (CAT) activity.

摘要

将三组海参(每组4.83±0.15克)暴露于四种名义浓度的膳食汞之一[0(对照组)、67.6、338和676毫克/千克干重,实际总汞分别为17.55、87.00、275.50、468.50毫克/千克;表3]中21天。肠道中的汞积累显示出最大的汞负荷(以77.96±1.20毫克汞/千克组织湿重计)。然而,存活率(SR)未受影响。676毫克汞/千克处理组后的体重增加显著低于对照组。676毫克汞/千克处理组的饲料转化率显著高于对照组。此外,海参的超氧化物歧化酶(SOD)和总抗氧化能力(T-AOC)随汞剂量增加而降低。676毫克汞/千克处理组的SOD、T-AOC和碱性磷酸酶显著低于对照组。然而,四组之间的酸性磷酸酶和过氧化氢酶(CAT)活性没有显著差异。

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