Bychkova V E, Semisotnov G V, Balobanov V A, Finkelstein A V
Institute of Protein Research, Pushchino, Moscow Region, 142290, Russia.
Biochemistry (Mosc). 2018 Jan;83(Suppl 1):S33-S47. doi: 10.1134/S0006297918140043.
In this review, we describe traditional systems where the molten globule (MG) state has been detected and give a brief description of the solution of Levinthal's paradox. We discuss new results obtained for MG-mediated folding of "nontraditional" proteins and a possible functional role of the MG. We also report new data on the MG, especially the dry molten globule.
在本综述中,我们描述了已检测到熔球态(MG)的传统体系,并简要介绍了莱文索尔悖论的解决方案。我们讨论了关于MG介导的“非传统”蛋白质折叠的新结果以及MG可能的功能作用。我们还报告了关于MG的新数据,特别是干燥熔球态的数据。