Carey Brian W, Harty James
Cork University Hospital Group, Wilton, Cork, Ireland.
MRCSI FRCSI (Trauma and Orthopaedics) Consultant Orthopaedic Surgeon, Cork University Hospital Group, Cork, Ireland.
J Orthop Surg Res. 2018 Mar 15;13(1):54. doi: 10.1186/s13018-018-0757-6.
The ATTUNE Knee by DePuy Synthes was introduced in 2013. It is designed to provide better range of motion and address patient-reported instability. The PFC Sigma Knee, an earlier prosthesis by DePuy Synthes, is a common knee replacement with a strong clinical track record. Our aim is to compare the outcomes after primary total knee replacement for end-stage knee osteoarthritis of the PFC and ATTUNE knee systems in 21 patients who each have prosthesis in opposite knees using WOMAC, Oxford Knee and SF-12 scores and evaluation of range of motion.
A review was carried out on 21 patients who underwent primary total knee replacement with both the ATTUNE and PFC knee systems. These were staged operations performed in the same institution and by the same surgeon. All cases were followed up for a minimum of 6 months. WOMAC, Oxford Knee and SF-12 scores, as well as knee range of motion were recorded preoperatively and at 6 months postoperatively.
There was a significant difference in pre- to 6-month post-operative outcomes in PFC and ATTUNE groups with regard to improvement in range of motion (10° ± 8 and 13° ± 11, respectively). There was also a significant improvement in WOMAC scores (PFC group) and Oxford Knee Scores (ATTUNE group) (8.9 ± 7.7 and 12.1 ± 8.4, respectively). There was a significant improvement in SF-12 Score in both groups (10.1 ± 9.3 for PFC and 15.8 ± 13.3 for ATTUNE). The minimum clinically important difference (MCID) in scoring systems at 6 months was reached by 6 patients in the PFC group and 12 in the ATTUNE group.
A significant difference was demonstrated in clinical outcome at 6 months postoperatively between PFC and ATTUNE knee systems in patients who underwent total knee arthroplasty with both prostheses. Superior results were recorded for the ATTUNE knee system.
德普伊辛迪思公司的ATTUNE膝关节假体于2013年推出。其设计旨在提供更好的活动范围并解决患者报告的不稳定问题。德普伊辛迪思公司早期的一款假体PFC Sigma膝关节是一种常见的膝关节置换产品，有着可靠的临床记录。我们的目的是比较21例终末期膝关节骨关节炎患者分别在双膝植入PFC和ATTUNE膝关节系统进行初次全膝关节置换后的结果，采用WOMAC、牛津膝关节评分和SF - 12评分以及活动范围评估。
对21例接受了ATTUNE和PFC膝关节系统初次全膝关节置换的患者进行回顾性研究。这些是在同一机构由同一位外科医生进行的分期手术。所有病例均随访至少6个月。记录术前及术后6个月时的WOMAC、牛津膝关节和SF - 12评分以及膝关节活动范围。
PFC组和ATTUNE组术前至术后6个月在活动范围改善方面（分别为10°±8和13°±11）存在显著差异。WOMAC评分（PFC组）和牛津膝关节评分（ATTUNE组）也有显著改善（分别为8.9±7.7和12.1±8.4）。两组的SF - 12评分均有显著改善（PFC组为10.1±9.3，ATTUNE组为15.8±13.3）。PFC组有6例患者、ATTUNE组有12例患者在6个月时达到了评分系统的最小临床重要差异（MCID）。
对于接受了两种假体全膝关节置换的患者，术后6个月时PFC和ATTUNE膝关节系统的临床结果存在显著差异。ATTUNE膝关节系统的结果更优。
