用于RAId的图形用户界面，RAId是一个具有精确统计功能的知识集成蛋白质组学分析套件。
A graphical user interface for RAId, a knowledge integrated proteomics analysis suite with accurate statistics.
作者信息
Joyce Brendan, Lee Danny, Rubio Alex, Ogurtsov Aleksey, Alves Gelio, Yu Yi-Kuo
机构信息
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD, 20894, USA.
出版信息
BMC Res Notes. 2018 Mar 15;11(1):182. doi: 10.1186/s13104-018-3289-6.
OBJECTIVE
RAId is a software package that has been actively developed for the past 10 years for computationally and visually analyzing MS/MS data. Founded on rigorous statistical methods, RAId's core program computes accurate E-values for peptides and proteins identified during database searches. Making this robust tool readily accessible for the proteomics community by developing a graphical user interface (GUI) is our main goal here.
RESULTS
We have constructed a graphical user interface to facilitate the use of RAId on users' local machines. Written in Java, RAId_GUI not only makes easy executions of RAId but also provides tools for data/spectra visualization, MS-product analysis, molecular isotopic distribution analysis, and graphing the retrieval versus the proportion of false discoveries. The results viewer displays and allows the users to download the analyses results. Both the knowledge-integrated organismal databases and the code package (containing source code, the graphical user interface, and a user manual) are available for download at https://www.ncbi.nlm.nih.gov/CBBresearch/Yu/downloads/raid.html .
目的
RAId是一个在过去10年中一直在积极开发的软件包，用于对串联质谱（MS/MS）数据进行计算和可视化分析。基于严格的统计方法，RAId的核心程序为数据库搜索过程中鉴定出的肽段和蛋白质计算准确的E值。通过开发图形用户界面（GUI），使这个强大的工具能够被蛋白质组学社区方便地使用，是我们在此的主要目标。
结果
我们构建了一个图形用户界面，以便于在用户本地机器上使用RAId。RAId_GUI用Java编写，不仅使RAId易于执行，还提供了数据/谱图可视化、MS产物分析、分子同位素分布分析以及绘制检索结果与错误发现比例关系图的工具。结果查看器显示并允许用户下载分析结果。知识整合的生物体数据库和代码包（包含源代码、图形用户界面和用户手册）可在https://www.ncbi.nlm.nih.gov/CBBresearch/Yu/downloads/raid.html 下载。
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