Asmat Shakila, Shaukat Fouzia, Asmat Raheela, Bakhat Hafiz Faiq Siddique Gul, Asmat Tauseef M
Department of Pediatrics, Sheikh Zayed Hospital, Lahore.
Department of Pediatrics, Bolan Medical College, Quetta.
J Coll Physicians Surg Pak. 2018 Mar;28(3):214-217. doi: 10.29271/jcpsp.2018.03.214.
To compare the efficacy of Saccharomyces boulardii and lactic acid producing probiotics in addition to usual treatment regimen to cure diarrhea among children (6 months to 5 years of age).
Randomized controlled trial.
Department of Pediatrics, Sheikh Zayed Hospital, Lahore, from February to July 2015.
Children suffering from acute diarrhea were orally administered Saccharomyces boulardii and lactic acid producing probiotics for 5 days. The efficacy of administered probiotics was monitored. Patients were given Saccharomyces boulardii and lactic acid producing probiotics randomly to remove the bias.
Two hundred patients randomly selected for trials; out of which, 100 were treated with Saccharomyces boulardii while the other 100 were supplemented with lactic acid concomitantly along with conventional diarrhea treatment. Results indicated that Saccharomyces boulardii treatment group has significantly higher efficacy rate (45%) compared to lactic acid producing probiotics (26%).
This study concluded that Saccharomyces boulardii has a better efficacy compared to lactic acid and may be adopted as a probiotic of choice.
比较布拉酵母菌和产乳酸益生菌在常规治疗方案基础上治疗6个月至5岁儿童腹泻的疗效。
随机对照试验。
2015年2月至7月，拉合尔谢赫扎耶德医院儿科。
对患有急性腹泻的儿童口服布拉酵母菌和产乳酸益生菌5天。监测所施用益生菌的疗效。为消除偏差，随机给予患者布拉酵母菌和产乳酸益生菌。
随机选择200名患者进行试验；其中，100名接受布拉酵母菌治疗，另外100名在常规腹泻治疗的同时补充乳酸。结果表明，布拉酵母菌治疗组的有效率（45%）显著高于产乳酸益生菌组（26%）。
本研究得出结论，布拉酵母菌比乳酸具有更好的疗效，可作为首选益生菌采用。
