Concurrent treatment of aplastic anemia/paroxysmal nocturnal hemoglobinuria syndrome with immunosuppressive therapy and eculizumab: a UK experience.
作者信息
Griffin Morag, Kulasekararaj Austin, Gandhi Sheyans, Munir Talha, Richards Stephen, Arnold Louise, Benson-Quarm Nana, Copeland Nicola, Duggins Isabel, Riley Kathryn, Hillmen Peter, Marsh Judith, Hill Anita
机构信息
Hematology department, St James University Hospital, Leeds, London, UK
Hematology department, King's college University Hospital, London, UK.
出版信息
Haematologica. 2018 Aug;103(8):e345-e347. doi: 10.3324/haematol.2017.183046. Epub 2018 Mar 15.
Abstract
摘要
相似文献
1
Concurrent treatment of aplastic anemia/paroxysmal nocturnal hemoglobinuria syndrome with immunosuppressive therapy and eculizumab: a UK experience.免疫抑制疗法联合依库珠单抗治疗再生障碍性贫血/阵发性睡眠性血红蛋白尿综合征：英国的经验
Haematologica. 2018 Aug;103(8):e345-e347. doi: 10.3324/haematol.2017.183046. Epub 2018 Mar 15.
2
Combined intensive immunosuppression and eculizumab for aplastic anemia in the context of hemolytic paroxysmal nocturnal hemoglobinuria: a retrospective analysis.
Bone Marrow Transplant. 2018 Jan;53(1):105-107. doi: 10.1038/bmt.2017.220. Epub 2017 Nov 13.
3
Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine.阵发性睡眠性血红蛋白尿症克隆在接受马抗胸腺细胞球蛋白加环孢素治疗的重型再生障碍性贫血患者中出现。
Haematologica. 2010 Jul;95(7):1075-80. doi: 10.3324/haematol.2009.017889.
4
Successful cholecystectomy in a patient with aplastic anemia-paroxysmal nocturnal hemoglobinuria during eculizumab treatment.在接受依库珠单抗治疗的再生障碍性贫血-阵发性夜间血红蛋白尿患者中成功实施胆囊切除术。
Ann Hematol. 2012 Dec;91(12):1987-8. doi: 10.1007/s00277-012-1514-2. Epub 2012 Jun 28.
5
Effectiveness of eculizumab in patients with paroxysmal nocturnal hemoglobinuria (PNH) with or without aplastic anemia in the International PNH Registry.国际阵发性睡眠性血红蛋白尿（PNH）注册研究中依库珠单抗在伴或不伴再生障碍性贫血的阵发性睡眠性血红蛋白尿（PNH）患者中的疗效
Am J Hematol. 2019 Jan;94(1):E37-E41. doi: 10.1002/ajh.25334. Epub 2018 Nov 25.
6
Effects of immunosuppressive therapy in a patient with aplastic anemia-paroxysmal nocturnal hemoglobinuria (AA-PNH) syndrome during ongoing eculizumab treatment.在接受依库珠单抗持续治疗期间，免疫抑制疗法对一名再生障碍性贫血 - 阵发性睡眠性血红蛋白尿（AA-PNH）综合征患者的影响。
Intern Med. 2014;53(2):125-8. doi: 10.2169/internalmedicine.53.0684. Epub 2012 Mar 1.
7
Effective eculizumab therapy followed by BMT in a boy with paroxysmal nocturnal hemoglobinuria.一名阵发性夜间血红蛋白尿男孩接受有效依库珠单抗治疗后进行骨髓移植。
Pediatr Int. 2015 Apr;57(2):e27-9. doi: 10.1111/ped.12522.
8
Horse anti-thymocyte globulin and eculizumab as concomitant therapeutic approach in an aplastic paroxysmal nocturnal hemoglobinuria patient: go or no-go?马抗胸腺细胞球蛋白和依库珠单抗联合治疗再生障碍性阵发性夜间血红蛋白尿患者：可行还是不可行？
Eur J Haematol. 2016 Oct;97(4):403-5. doi: 10.1111/ejh.12754. Epub 2016 Apr 26.
9
Erythopoietin treatment during complement inhibition with eculizumab in a patient with paroxysmal nocturnal hemoglobinuria.依库珠单抗抑制补体治疗阵发性睡眠性血红蛋白尿症患者期间的促红细胞生成素治疗
Haematologica. 2007 Mar;92(3):e31-3. doi: 10.3324/haematol.10836.
10
Successful use of eculizumab in a pediatric patient treated for paroxysmal nocturnal hemoglobinuria.依库珠单抗成功用于治疗阵发性夜间血红蛋白尿的儿科患者。
J Pediatr Hematol Oncol. 2012 Nov;34(8):e346-8. doi: 10.1097/MPH.0b013e318258079a.
引用本文的文献
1
Severe renal haemosiderosis in a patient with untreated paroxysmal nocturnal haemoglobinuria: a case report.一例未经治疗的阵发性夜间血红蛋白尿患者的严重肾含铁血黄素沉着症：病例报告
BMC Nephrol. 2025 Aug 5;26(1):435. doi: 10.1186/s12882-025-04343-5.
2
What are the most important quality of life domains for patients with aplastic anemia and paroxysmal nocturnal hemoglobinuria?再生障碍性贫血和阵发性夜间血红蛋白尿患者最重要的生活质量领域有哪些？
Ann Hematol. 2025 May;104(5):3073-3075. doi: 10.1007/s00277-025-06377-z. Epub 2025 Apr 29.
3
Current status and perspectives of hematopoietic cell transplantation in patients with paroxysmal nocturnal hemoglobinuria.阵发性睡眠性血红蛋白尿症患者造血细胞移植的现状与展望
Front Immunol. 2025 Jan 7;15:1521484. doi: 10.3389/fimmu.2024.1521484. eCollection 2024.
4
Monitoring and Treatment of Paroxysmal Nocturnal Hemoglobinuria in Patients with Aplastic Anemia in Asia: An Expert Consensus.亚洲再生障碍性贫血患者阵发性睡眠性血红蛋白尿症的监测和治疗：专家共识。
Int J Mol Sci. 2024 Nov 13;25(22):12160. doi: 10.3390/ijms252212160.
5
Germline variants in acquired aplastic anemia: current knowledge and future perspectives.获得性再生障碍性贫血中的种系变异：当前的认识和未来的展望。
Haematologica. 2024 Sep 1;109(9):2778-2789. doi: 10.3324/haematol.2023.284312.
6
Complement Inhibition in Paroxysmal Nocturnal Hemoglobinuria (PNH): A Systematic Review and Expert Opinion from Central Europe on Special Patient Populations.阵发性睡眠性血红蛋白尿症（PNH）中的补体抑制：中欧特殊患者人群的系统评价和专家意见。
Adv Ther. 2023 Jun;40(6):2752-2772. doi: 10.1007/s12325-023-02510-4. Epub 2023 Apr 18.
7
Attack of the Clones: A Patient With Untreated Aplastic Anemia Presenting With Classical Paroxysmal Nocturnal Hemoglobinuria.《克隆人的进攻》：一名未经治疗的再生障碍性贫血患者出现典型阵发性夜间血红蛋白尿。
Cureus. 2023 Jan 23;15(1):e34093. doi: 10.7759/cureus.34093. eCollection 2023 Jan.
8
Low Rate of Clinically Evident Extravascular Hemolysis in Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with a Complement C5 Inhibitor: Results from a Large, Multicenter, US Real-World Study.补体C5抑制剂治疗阵发性睡眠性血红蛋白尿患者临床明显血管外溶血发生率低：一项大型多中心美国真实世界研究的结果
J Blood Med. 2022 Aug 12;13:425-437. doi: 10.2147/JBM.S361863. eCollection 2022.
9
The importance of terminal complement inhibition in paroxysmal nocturnal hemoglobinuria.终末补体抑制在阵发性夜间血红蛋白尿中的重要性。
Ther Adv Hematol. 2022 May 30;13:20406207221091046. doi: 10.1177/20406207221091046. eCollection 2022.
10
Primary myelofibrosis with concurrent paroxysmal nocturnal haemoglobinuria presenting with erectile dysfunction.原发性骨髓纤维化合并阵发性夜间血红蛋白尿并伴有勃起功能障碍
Oxf Med Case Reports. 2022 May 23;2022(5):omac047. doi: 10.1093/omcr/omac047. eCollection 2022 May.
本文引用的文献
1
Hematopoietic stem cell transplantation for patients with paroxysmal nocturnal hemoglobinuria previously treated with eculizumab: a retrospective study of 21 patients from SFGM-TC centers.接受过依库珠单抗治疗的阵发性睡眠性血红蛋白尿症患者的造血干细胞移植：一项对SFGM-TC中心21例患者的回顾性研究
Haematologica. 2018 Mar;103(3):e103-e105. doi: 10.3324/haematol.2017.182360. Epub 2017 Dec 21.
2
Combined intensive immunosuppression and eculizumab for aplastic anemia in the context of hemolytic paroxysmal nocturnal hemoglobinuria: a retrospective analysis.
Bone Marrow Transplant. 2018 Jan;53(1):105-107. doi: 10.1038/bmt.2017.220. Epub 2017 Nov 13.
3
Guidelines for the diagnosis and management of adult aplastic anaemia.成人再生障碍性贫血诊断与治疗指南。
Br J Haematol. 2016 Jan;172(2):187-207. doi: 10.1111/bjh.13853. Epub 2015 Nov 16.
4
Current outcome of HLA identical sibling versus unrelated donor transplants in severe aplastic anemia: an EBMT analysis.严重再生障碍性贫血中 HLA 全相合同胞供者与无关供者移植的当前结局：一项欧洲血液与骨髓移植组（EBMT）分析
Haematologica. 2015 May;100(5):696-702. doi: 10.3324/haematol.2014.115345. Epub 2015 Jan 23.
5
Effects of immunosuppressive therapy in a patient with aplastic anemia-paroxysmal nocturnal hemoglobinuria (AA-PNH) syndrome during ongoing eculizumab treatment.在接受依库珠单抗持续治疗期间，免疫抑制疗法对一名再生障碍性贫血 - 阵发性睡眠性血红蛋白尿（AA-PNH）综合征患者的影响。
Intern Med. 2014;53(2):125-8. doi: 10.2169/internalmedicine.53.0684. Epub 2012 Mar 1.
6
Allogeneic stem cell transplantation in paroxysmal nocturnal hemoglobinuria.阵发性睡眠性血红蛋白尿症的异基因造血干细胞移植。
Haematologica. 2012 Nov;97(11):1666-73. doi: 10.3324/haematol.2012.062828. Epub 2012 Jun 11.
7
Paroxysmal nocturnal hemoglobinuria: natural history of disease subcategories.阵发性夜间血红蛋白尿：疾病亚类的自然史
Blood. 2008 Oct 15;112(8):3099-106. doi: 10.1182/blood-2008-01-133918. Epub 2008 Jun 5.
8
Minor population of CD55-CD59- blood cells predicts response to immunosuppressive therapy and prognosis in patients with aplastic anemia.CD55-CD59-血细胞亚群可预测再生障碍性贫血患者对免疫抑制治疗的反应及预后。
Blood. 2006 Feb 15;107(4):1308-14. doi: 10.1182/blood-2005-06-2485. Epub 2005 Sep 22.
10
Natural history of paroxysmal nocturnal hemoglobinuria.阵发性夜间血红蛋白尿的自然病史。
N Engl J Med. 1995 Nov 9;333(19):1253-8. doi: 10.1056/NEJM199511093331904.
Zotero 插件