Department of Internal Neurology, Xuzhou Third People's Hospital, 131 Huancheng Road, Xuzhou, China.
Department of Control and Prevention of Chronic Non-communicable Diseases, Xuzhou Center for Disease Control and Prevention, 142 West Erhuan Road, Xuzhou, Jiangsu, 221000, China.
BMC Public Health. 2018 Mar 16;18(1):364. doi: 10.1186/s12889-018-5276-1.
To describe the prevalence of alcohol dependence and to explore the relationship between alcohol dependence and newly detected hypertension in China.
A multistage stratified cluster sampling method was used to obtain samples from February to June 2013. The Michigan Alcoholism Screening Test was used to estimate alcohol dependence level. A standard questionnaire measured other independent variables. Enumeration data were analyzed using chi-square; quantitative data were analyzed using t-tests. Spearman correlation analysis and multivariate logistic regression analysis were performed to identify the relationship between alcohol dependence and hypertension.
The alcohol dependence rate was 11.56%; 22.02% of males (3854/17501) and 1.74% of females (324/18656) were classified as alcohol dependent. The newly detected hypertension rate was 9.46% (3422/36157). Significant associations were found between alcohol dependence levels and blood pressure (P < 0.01). Alcohol dependence was positively correlated with systolic blood pressure (r = 0.071, P < 0.01) and diastolic blood pressure (r = 0.077, P < 0.01) and was an independent risk factor for hypertension after adjusting for confounders (low alcohol dependence: odds ratio [OR] = 1.44, 95% confidence intervals [CI] = 1.14-1.81, P < 0.01; light alcohol dependence: OR = 1.35, 95% CI = 1.11-1.64, P < 0.01; medium alcohol dependence: OR = 1.83, 95% CI = 1.40-2.41, P < 0.01).
Alcohol dependence was high and associated with hypertension. Health education and precautions against alcoholism should be implemented in Xuzhou city.
描述中国酒精依赖的流行情况，并探讨酒精依赖与新检出高血压之间的关系。
采用多阶段分层聚类抽样方法，于 2013 年 2 月至 6 月抽取样本。采用密歇根酒精依赖筛查测试评估酒精依赖水平。采用标准问卷测量其他自变量。采用卡方检验分析计数资料，采用 t 检验分析定量资料。采用 Spearman 相关分析和多因素 logistic 回归分析来确定酒精依赖与高血压之间的关系。
酒精依赖率为 11.56%；男性中 22.02%（3854/17501）和女性中 1.74%（324/18656）被归类为酒精依赖者。新检出高血压率为 9.46%（3422/36157）。酒精依赖水平与血压之间存在显著相关性（P<0.01）。酒精依赖与收缩压（r=0.071，P<0.01）和舒张压（r=0.077，P<0.01）呈正相关，且在调整混杂因素后，是高血压的独立危险因素（轻度酒精依赖：比值比[OR] = 1.44，95%置信区间[CI] = 1.14-1.81，P<0.01；轻度酒精依赖：OR = 1.35，95% CI = 1.11-1.64，P<0.01；中度酒精依赖：OR = 1.83，95% CI = 1.40-2.41，P<0.01）。
酒精依赖率较高，且与高血压相关。徐州市应开展健康教育和预防酒精中毒措施。
