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新生儿听力障碍危险因素的识别:一项基于医院的研究。

Identification of risk factors for hearing impairment in newborns: a hospital based study.

作者信息

Hrnčić Nermin

机构信息

Department of Otorhinolaryngology, Cantonal Hospital Zenica, Bosnia and Herzegovina.

出版信息

Med Glas (Zenica). 2018 Feb 1;15(1):29-36. doi: 10.17392/943-18.

DOI:10.17392/943-18
PMID:29549688
Abstract

Aim To identify risk factors for hearing impairment presented in neonates born in Cantonal Hospital Zenica (CHZ) and to estimate their influence on outcome of hearing tests in Newborn Hearing Screening (NHS). Methods Retrospective-prospective study was done at the Department of Gynaecology and Maternity. The NHS was performed with transitory evoked otoacoustic emissions (TEOAE) during a six-month period using "Titan" device (Interacoustics, Denmark). The questionnaire was written for the purpose of getting more structured basic information about every newborn and to identify risk factors for hearing impairment. Chi-square test was used to investigate the difference between experimental and control group refer incidence. Results A total of 1217 newborns was screened for hearing impairment of which 259 (21.28%) with one or more known risk factors for hearing impairment. The following risk factors for hearing impairment were identified during the study period: family history of permanent childhood hearing impairment in 42 (3.45%) newborns, prematurity in 39 (3.21%), low APGAR scores in 29 (2.40%), asphyxia in 31 (2.55%), hyperbilirubinemia in 41 (3.37%), admission of ototoxic medication (aminoglycosides) after birth in 155 (12.74%). Conclusion There were many serious risk factors for hearing loss identified in this study. Identification of risk factors for hearing impairment in neonates is necessary because a follow up of the children with risk factors is very important.

摘要

目的 确定泽尼察州立医院(CHZ)出生的新生儿出现听力障碍的风险因素,并评估这些因素对新生儿听力筛查(NHS)中听力测试结果的影响。方法 在妇产科进行回顾性-前瞻性研究。使用“泰坦”设备(丹麦Interacoustics公司),通过瞬态诱发耳声发射(TEOAE)在六个月内进行新生儿听力筛查。编写问卷是为了获取有关每个新生儿更结构化的基本信息,并确定听力障碍的风险因素。采用卡方检验来研究实验组和对照组参考发病率之间的差异。结果 共对1217名新生儿进行了听力障碍筛查,其中259名(21.28%)有一个或多个已知的听力障碍风险因素。在研究期间确定了以下听力障碍风险因素:42名(3.45%)新生儿有永久性儿童听力障碍家族史,39名(3.21%)早产,29名(2.40%)阿氏评分低,31名(2.55%)窒息,41名(3.37%)高胆红素血症,155名(12.74%)出生后使用耳毒性药物(氨基糖苷类)。结论 本研究确定了许多导致听力损失的严重风险因素。识别新生儿听力障碍的风险因素很有必要,因为对有风险因素的儿童进行随访非常重要。

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