Burke P M, Herrmann J B, Cutler B S
J Cardiovasc Surg (Torino). 1987 Jul-Aug;28(4):420-6.
Aortobifemoral bypass procedures were performed on 42 patients with the hypoplastic aortoiliac syndrome over an eight year period. During the first five years, 22 patients had either a 13 X 6.5 mm or a 14 X 7 mm knitted Dacron graft and served as historic controls for a second group of 20 others who had 14 X 7 mm grafts of expanded polytetrafluoroethylene (PTFE), during the last three years of the study. Although the two groups were neither concurrent nor randomized, they were nonetheless well matched with regard to age, sex, risk factors, indications for operations, distribution and severity of distal occlusive disease, and type of distal anastomosis. There was only one early graft limb occlusion in the PTFE group after a median follow-up of 14 months, compared to nine occlusions and one amputation in the Dacron group after a median follow-up of 26.2 months. The cumulative patency of the PTFE grafts was 95% at four years compared to only 52% for Dacron (p = 0.11). If the single postoperative occlusion which occurred in each group is excluded, then the difference in patency rates bordered on statistical significance (p = 0.06). Inclusion of the profunda femoris orifice in the distal anastomosis was also found to be an important factor contributing to long-term patency which approached statistical significance (p = 0.075). The configuration of the proximal aortic anastomosis (end to end vs. end to side), or the concomitant use of lumbar sympathectomy or the postoperative infusion of Dextran did not have a statistically significant influence on patency.(ABSTRACT TRUNCATED AT 250 WORDS)
在八年时间里,对42例患有主动脉髂动脉发育不全综合征的患者实施了主动脉双股动脉搭桥手术。在最初的五年中,22例患者使用了13×6.5毫米或14×7毫米的针织涤纶移植物,并作为另外20例在研究的最后三年使用14×7毫米膨体聚四氟乙烯(PTFE)移植物患者的历史对照。尽管两组既不是同期的也不是随机分组的,但在年龄、性别、危险因素、手术指征、远端闭塞性疾病的分布和严重程度以及远端吻合的类型方面匹配良好。PTFE组在中位随访14个月后仅出现1例早期移植物肢体闭塞,而涤纶组在中位随访26.2个月后出现9例闭塞和1例截肢。PTFE移植物在四年时的累积通畅率为95%,而涤纶移植物仅为52%(p = 0.11)。如果排除每组中发生的单例术后闭塞,则通畅率的差异接近统计学显著性(p = 0.06)。在远端吻合术中纳入股深动脉开口也被发现是有助于长期通畅的一个重要因素,接近统计学显著性(p = 0.075)。近端主动脉吻合的构型(端端吻合与端侧吻合)、同时使用腰交感神经切除术或术后输注右旋糖酐对通畅率没有统计学上的显著影响。(摘要截短为250字)