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便携式平板电脑与 Humphrey 视野分析仪的 6 个月纵向比较。

Six-month Longitudinal Comparison of a Portable Tablet Perimeter With the Humphrey Field Analyzer.

机构信息

Department of Optometry & Vision Sciences, The University of Melbourne, Parkville, Victoria, Australia.

Department of Ophthalmology, Cambridge University Hospitals NHS Foundation Trust, Cambridgeshire, United Kingdom.

出版信息

Am J Ophthalmol. 2018 Jun;190:9-16. doi: 10.1016/j.ajo.2018.03.009. Epub 2018 Mar 14.

Abstract

PURPOSE

To establish the medium-term repeatability of the iPad perimetry app Melbourne Rapid Fields (MRF) compared to Humphrey Field Analyzer (HFA) 24-2 SITA-standard and SITA-fast programs.

DESIGN

Multicenter longitudinal observational clinical study.

METHODS

Sixty patients (stable glaucoma/ocular hypertension/glaucoma suspects) were recruited into a 6-month longitudinal clinical study with visits planned at baseline and at 2, 4, and 6 months. At each visit patients undertook visual field assessment using the MRF perimetry application and either HFA SITA-fast (n = 21) or SITA-standard (n = 39). The primary outcome measure was the association and repeatability of mean deviation (MD) for the MRF and HFA tests. Secondary measures were the point-wise threshold and repeatability for each test, as well as test time.

RESULTS

MRF was similar to SITA-fast in speed and significantly faster than SITA-standard (MRF 4.6 ± 0.1 minutes vs SITA-fast 4.3 ± 0.2 minutes vs SITA-standard 6.2 ± 0.1 minutes, P < .001). Intraclass correlation coefficients (ICC) between MRF and SITA-fast for MD at the 4 visits ranged from 0.71 to 0.88. ICC values between MRF and SITA-standard for MD ranged from 0.81 to 0.90. Repeatability of MRF MD outcomes was excellent, with ICC for baseline and the 6-month visit being 0.98 (95% confidence interval: 0.96-0.99). In comparison, ICC at 6-month retest for SITA-fast was 0.95 and SITA-standard 0.93. Fewer points changed with the MRF, although for those that did, the MRF gave greater point-wise variability than did the SITA tests.

CONCLUSIONS

MRF correlated strongly with HFA across 4 visits over a 6-month period, and has good test-retest reliability. MRF is suitable for monitoring visual fields in settings where conventional perimetry is not readily accessible.

摘要

目的

与 Humphrey 视野分析仪(HFA)24-2 SITA 标准和 SITA 快速程序相比,建立 iPad 视野计 Melbourne Rapid Fields(MRF)的中期重复性。

设计

多中心纵向观察性临床研究。

方法

60 名(稳定青光眼/高眼压/青光眼疑似患者)患者参与了一项 6 个月的纵向临床研究,计划在基线和 2、4 和 6 个月时进行随访。在每次随访中,患者使用 MRF 视野计应用程序和 HFA SITA 快速(n=21)或 SITA 标准(n=39)进行视野评估。主要观察指标是 MRF 和 HFA 测试的平均偏差(MD)的相关性和重复性。次要指标是每个测试的逐点阈值和重复性,以及测试时间。

结果

MRF 在速度上与 SITA 快速相似,明显快于 SITA 标准(MRF 4.6±0.1 分钟 vs SITA 快速 4.3±0.2 分钟 vs SITA 标准 6.2±0.1 分钟,P<.001)。在 4 次随访中,MRF 与 SITA 快速的 MD 的组内相关系数(ICC)范围为 0.71 至 0.88。MRF 与 SITA 标准的 MD 的 ICC 值范围为 0.81 至 0.90。MRF MD 结果的重复性极好,基线和 6 个月随访的 ICC 为 0.98(95%置信区间:0.96-0.99)。相比之下,SITA 快速的 6 个月复测 ICC 为 0.95,SITA 标准为 0.93。MRF 的变化点较少,尽管对于那些变化点,MRF 比 SITA 测试具有更大的逐点变异性。

结论

在 6 个月的时间内,MRF 在 4 次随访中与 HFA 高度相关,并且具有良好的测试-再测试可靠性。MRF 适用于在常规视野检查不易获得的情况下监测视野。

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