Department of Neonatology, Rumah Sakit Anak dan Bunda Harapan Kita (Harapan Kita Women and Children Hospital), West Jakarta, Indonesia.
Department of Opthalmology, Rumah Sakit Anak dan Bunda Harapan Kita (Harapan Kita Women and Children Hospital), West Jakarta, Indonesia.
Arch Dis Child. 2018 Jun;103(6):619-621. doi: 10.1136/archdischild-2017-314094. Epub 2018 Mar 17.
Retinopathy of prematurity (ROP) is a well-known complication in preterm infants. Data on the incidence of ROP in Indonesia, in relation to birth weight (BW) and gestational age (GA), are limited.
To report the incidence of ROP in one of the oldest and largest neonatal intensive care unit (NICU) in Indonesia.
We studied the incidence and severity of ROP in inborn infants with a BW of ≤1500 g and/or GA of ≤32 weeks, who were admitted to the NICU of Harapan Kita Women and Children Hospital, Jakarta. In addition, infants with a higher BW and GA, receiving more than 40% oxygen for a longer period, were screened.
In 2005-2015, 182 infants were born with a BW of <1000 g and 437 with a weight of 1000-1500 g. In the <1000 g group, 27 (46%) of the screened infants showed no ROP, 22 (37%) showed ROP 1-2 and 10 (17%) showed ROP 3-5. In the 1000-1500 g group, 172 (68%) were without ROP, 71 (28%) with ROP 1-2 and nine (4%) with ROP 3-5. Twenty-two (13%) of the 163 screened infants weighing 1500-2000 g showed ROP 1-2 and two (1.2%) had ROP 3-5. Eight (18%) of the 44 screened infants born with a BW of more than 2000 g showed ROP 1-2 and none showed ROP 3-5.
The total incidence of ROP as well as severe ROP in infants with a BW of <1000 g and 1000-1500 g in our NICU is higher than in a developed country. ROP in Indonesia is also seen in infants with a BW of 1500-2500 g. Increasing the awareness of the risks of oxygen as well as better equipment to monitor oxygen delivery is essential.
早产儿视网膜病变（ROP）是早产儿的一种常见并发症。在印度尼西亚，与出生体重（BW）和胎龄（GA）相关的数据有限。
报告印度尼西亚最大和最古老的新生儿重症监护病房（NICU）之一的 ROP 发生率。
我们研究了在雅加达哈拉潘基塔妇女儿童医院 NICU 住院的 BW≤1500g 和/或 GA≤32 周的早产儿的 ROP 发生率和严重程度。此外，还对 BW 和 GA 较高、接受超过 40%氧气且时间较长的婴儿进行了筛查。
2005-2015 年，182 名 BW<1000g 的婴儿和 437 名 BW1000-1500g 的婴儿出生。在 BW<1000g 组中，27 名（46%）筛查婴儿无 ROP，22 名（37%）ROP 1-2 期，10 名（17%）ROP 3-5 期。在 BW1000-1500g 组中，172 名（68%）无 ROP，71 名（28%）ROP 1-2 期，9 名（4%）ROP 3-5 期。22 名（13%）BW1500-2000g 的筛查婴儿 ROP 1-2 期，2 名（1.2%）ROP 3-5 期。44 名 BW>2000g 筛查婴儿中，8 名（18%）ROP 1-2 期，无 3-5 期。
BW<1000g 和 1000-1500g 的婴儿中 ROP 总发生率以及严重 ROP 的发生率高于发达国家。印度尼西亚也可见 BW1500-2500g 的婴儿发生 ROP。提高对氧气风险的认识以及更好的氧气输送监测设备是必要的。
