Parad Richard B
Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, 75 Francis St., Rm. CWN418, Boston, MA, 02115, USA.
Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.
Pediatr Radiol. 2018 Apr;48(4):524-530. doi: 10.1007/s00247-017-4002-y. Epub 2018 Mar 17.
On Dec. 16, 2016, the U.S. Food and Drug Administration (FDA) released a warning regarding the potential neurotoxicity of anesthesia and sedation agents on the developing brain in children younger than 3 years and in women during their 3rd trimester of pregnancy. These concerns have relevance to the pediatric radiologist who must take into consideration how the child's state might impact image quality. In this review the author provides background on the special concerns in the potentially highest-risk group, pre-term and term neonates, and provides guidance and rationale for the avoidance of sedation in procedural imaging of the newborn.
2016年12月16日，美国食品药品监督管理局（FDA）发布了一项警告，指出麻醉和镇静剂对3岁以下儿童以及妊娠晚期女性发育中的大脑可能存在神经毒性。这些问题与儿科放射科医生相关，他们必须考虑儿童的状态如何影响图像质量。在本综述中，作者介绍了潜在最高风险组（早产儿和足月儿）的特殊关注点背景，并为新生儿程序性成像中避免使用镇静剂提供了指导和依据。
