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无症状肾结石——治疗还是不治疗

Asymptomatic Renal Stones-to Treat or Not to Treat.

作者信息

Streeper Necole M

机构信息

Division of Urology, Penn State Milton S. Hershey Medical Center, Mail Code H055, 500 University Drive, PO Box 850, Hershey, PA, 17033-0850, USA.

出版信息

Curr Urol Rep. 2018 Mar 17;19(5):29. doi: 10.1007/s11934-018-0782-3.

DOI:10.1007/s11934-018-0782-3
PMID:29550897
Abstract

PURPOSE OF REVIEW

There are no current guidelines on the optimal management of asymptomatic renal stones. This review summarizes the current literature, focusing on more recent studies that have been done to grow the body of evidence on this topic.

RECENT FINDINGS

Recent studies have found that stone size is a significant predictor of need for future surgical intervention, with > 7 mm for pediatric population and > 4 mm for residual fragments after both PNL and ureteroscopy (URS). The role of URS has been better defined with a recent RCT concluding that URS and SWL had comparable outcomes for an asymptomatic lower pole stone < 1 cm. The treatment decision for asymptomatic renal stones should take into consideration a variety of relevant patient and stone factors; however, ultimately, a shared decision-making approach should be used. In the properly counseled patient, active surveillance or prophylactic surgical intervention may be appropriate.

摘要

综述目的

目前尚无关于无症状肾结石最佳管理的指南。本综述总结了当前文献,重点关注近期为增加该主题证据而开展的研究。

最新发现

近期研究发现,结石大小是未来需要手术干预的重要预测因素,儿童患者结石直径>7mm,经皮肾镜取石术(PNL)和输尿管镜检查(URS)后残留碎片直径>4mm。一项近期的随机对照试验得出结论,对于直径<1cm的无症状下极结石,URS和体外冲击波碎石术(SWL)的疗效相当,从而更好地明确了URS的作用。无症状肾结石的治疗决策应考虑多种相关的患者和结石因素;然而,最终应采用共同决策的方法。对于得到适当咨询的患者,主动监测或预防性手术干预可能是合适的。

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Urologists' opinion on treating asymptomatic stones: Would we treat ourselves as we treat our patients? Survey from European Association of Urology, Young Academic Urologists, Endourology and Urolithiasis working party.泌尿科医生对治疗无症状结石的看法:我们会像治疗患者一样对待自己吗?来自欧洲泌尿外科学会、青年泌尿外科医生、内镜泌尿外科和尿石症工作组的调查。
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本文引用的文献

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What happens to asymptomatic lower pole kidney stones smaller than 10 mm in children during watchful waiting?在观察等待期间,儿童中小于10毫米的无症状下极肾结石会怎样?
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Natural History of Residual Fragments After Percutaneous Nephrolithotomy: Evaluation of Factors Related to Clinical Events and Intervention.经皮肾镜取石术后残余结石碎片的自然史:与临床事件和干预相关因素的评估
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Relocation of lower pole renal stones helps improve the stone-free rate during flexible ureteroscopy with a low complication rate.
低位肾结石的移位有助于提高软镜碎石术的结石清除率,且并发症发生率低。
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5
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J Urol. 2016 Apr;195(4 Pt 1):982-6. doi: 10.1016/j.juro.2015.11.009. Epub 2015 Nov 14.
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EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis.EAU 指南:尿石症的诊断和保守治疗管理。
Eur Urol. 2016 Mar;69(3):468-74. doi: 10.1016/j.eururo.2015.07.040. Epub 2015 Aug 28.
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Shared decision making: why do patients choose ureteroscopy?共同决策:患者为何选择输尿管镜检查?
Urolithiasis. 2016 Apr;44(2):167-72. doi: 10.1007/s00240-015-0806-0. Epub 2015 Jul 25.
8
The natural history of nonobstructing asymptomatic renal stones managed with active surveillance.无症状非梗阻性肾结石行主动监测管理的自然病程。
J Urol. 2015 Apr;193(4):1265-9. doi: 10.1016/j.juro.2014.11.056. Epub 2014 Nov 15.
9
Asymptomatic lower pole small renal stones: shock wave lithotripsy, flexible ureteroscopy, or observation? A prospective randomized trial.无症状性下极小肾结石:冲击波碎石术、软性输尿管镜检查还是观察等待?一项前瞻性随机试验。
Urology. 2015 Jan;85(1):33-7. doi: 10.1016/j.urology.2014.08.023. Epub 2014 Oct 18.
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