Yin Zhiwei, Peters Stephen, Chokshi Ravi, Heller Debra
1 Rutgers-New Jersey Medical School, Newark, NJ, USA.
Int J Surg Pathol. 2018 Sep;26(6):578-580. doi: 10.1177/1066896918763547. Epub 2018 Mar 19.
Ovarian clear cell adenofibroma is uncommon, and borderline clear cell adenofibroma (low malignant potential) is extremely rare. Borderline clear cell adenofibromas may represent the precursor lesion of clear cell adenocarcinoma of the ovary, but this has not been established. We present a case of a woman in her mid-50s with a clear cell adenofibroma ranging from benign to borderline to frankly invasive. While some clear cell adenocarcinomas are thought to arise from endometriosis, this range of findings supports the theory that some ovarian clear cell adenocarcinomas originate from borderline tumors.
卵巢透明细胞腺纤维瘤并不常见，而交界性透明细胞腺纤维瘤（低恶性潜能）极为罕见。交界性透明细胞腺纤维瘤可能是卵巢透明细胞腺癌的前驱病变，但这一点尚未得到证实。我们报告一例50多岁女性患有透明细胞腺纤维瘤，其病理表现从良性到交界性再到明显的浸润性。虽然一些透明细胞腺癌被认为起源于子宫内膜异位症，但这一系列的发现支持了一些卵巢透明细胞腺癌起源于交界性肿瘤的理论。
