Cormier R, Poliquin J F, Goyette B, Shariatmadar A
J Otolaryngol. 1987 Mar;16(2):67-70.
The mixed lymphocyte response (MLR) of the guinea pig was assessed using skin allografts placed in the tympanic cavity, in comparison to the MLR obtained with allografts sutured on the backs of these animals. The MLR obtained from middle ear stimulation was transient. It was not altered by previous systemic immunization, nor did it alter the subsequent MLR obtained when the allografts were implanted on the backs of the guinea pigs. Immunoperoxidase and hematoxylin/eosin stainings of the tympanic allografts were also attempted to make a pathological correlation. Our findings are compatible with other observations of mucosal immune systems.
与将同种异体移植物缝合在豚鼠背部所获得的混合淋巴细胞反应（MLR）相比，利用置于鼓室内的皮肤同种异体移植物评估了豚鼠的MLR。从中耳刺激获得的MLR是短暂的。它不会因先前的全身免疫而改变，也不会改变当同种异体移植物植入豚鼠背部时随后获得的MLR。还尝试对鼓室同种异体移植物进行免疫过氧化物酶和苏木精/伊红染色，以建立病理相关性。我们的发现与对黏膜免疫系统的其他观察结果一致。
