Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland; Central Finland Health Care District, Jyväskylä, Finland.
Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland.
Prog Cardiovasc Dis. 2018 Mar-Apr;60(6):635-641. doi: 10.1016/j.pcad.2018.03.005. Epub 2018 Mar 16.
Both cardiorespiratory fitness (CRF) and frequency of sauna bathing (FSB) are each strongly and independently associated with sudden cardiac death (SCD) risk. However, the combined effect of CRF and FSB on SCD risk has not been previously investigated. We evaluated the joint impact of CRF and FSB on the risk of SCD in the Kuopio Ischemic Heart Disease prospective cohort study of 2291 men aged 42-61 years at recruitment. Objectively measured CRF and self-reported sauna bathing habits were assessed at baseline. CRF was categorized as low and high (median cutoffs) and FSB as low and high (defined as ≤2 and 3-7 sessions/week respectively). Multivariable adjusted hazard ratios (HRs) with confidence intervals (CIs) were calculated for SCD. During a median follow-up of 26.1 years, 226 SCDs occurred. Comparing high vs low CRF, the HR (95% CIs) for SCD in analysis adjusted for several established risk factors was 0.48 (0.34-0.67). Comparing high vs low FSB, the corresponding HR was 0.67 (0.46-0.98). Compared to men with low CRF & low FSB, the multivariate-adjusted HRs of SCD for the following groups: high CRF & high FSB; high CRF & low FSB; and low CRF & high FSB were 0.31 (0.16-0.63), 0.49 (0.34-0.70), and 0.71 (0.45-1.10) respectively. In a general male Caucasian population, the combined effect of high aerobic fitness (as measured by CRF) and frequent sauna baths is associated with a substantially lowered risk of future SCD compared with high CRF or frequent sauna bathing alone.
心肺适能（CRF）和桑拿浴频率（FSB）都与心脏性猝死（SCD）风险有强烈的独立相关性。然而，CRF 和 FSB 对 SCD 风险的综合影响尚未被研究过。我们评估了心肺适能和桑拿浴频率在库奥皮奥缺血性心脏病前瞻性队列研究中的联合影响，该研究纳入了 2291 名年龄在 42-61 岁的男性。在招募时，使用客观测量的心肺适能和自我报告的桑拿浴习惯进行评估。CRF 分为低和高（中位数切点），FSB 分为低和高（分别定义为每周 2 次和 3-7 次）。计算多变量调整后的风险比（HR）及其置信区间（CI），以评估 SCD。在中位随访 26.1 年期间，发生了 226 例 SCD。在调整了多个既定风险因素的分析中，与低 CRF 相比，高 CRF 与 SCD 的 HR（95%CI）为 0.48（0.34-0.67）。与低 FSB 相比，高 FSB 的相应 HR 为 0.67（0.46-0.98）。与低 CRF 和低 FSB 的男性相比，高 CRF 和高 FSB、高 CRF 和低 FSB 以及低 CRF 和高 FSB 的多变量调整后的 SCD 风险 HR 分别为 0.31（0.16-0.63）、0.49（0.34-0.70）和 0.71（0.45-1.10）。在一般的男性白种人群中，高有氧适能（通过 CRF 测量）和频繁桑拿浴的联合作用与未来 SCD 风险的显著降低相关，与高 CRF 或频繁桑拿浴单一因素相比。
J Psychiatr Res. 2024-7
JAMA Intern Med. 2015-4
Zotero 插件