Use-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Use-inspired Biomaterials & Integrated Nano Delivery (U-BiND) Systems Laboratory, Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI 48201, USA.
Drug Discov Today. 2018 Jul;23(7):1344-1356. doi: 10.1016/j.drudis.2018.03.003. Epub 2018 Mar 15.
Nanoparticle library engineered with tunable size, shape, and geometry will provide a better idea of targeting multicomponent of tumor microenvironment consisting of epithelial cells, tumor hypoxia, tumor immune cells and angiogenic blood vessels.
通过工程设计具有可调尺寸、形状和几何形状的纳米粒子库,将更好地了解针对由上皮细胞、肿瘤缺氧、肿瘤免疫细胞和血管生成血管组成的肿瘤微环境的多成分靶向作用。