Konstantinov B A, Mikaelian A L, Tkachenko V M, Levina G A, Agababian K R
Kardiologiia. 1987 Apr;27(4):61-4.
A study of 61 patients with congenital stenosis of the aortic ostium has shown that left ventricular myocardial dysfunction is related to the extent of myocardial hypertrophy. Progressive discrepancy between growing left ventricular myocardial hypertrophy and its blood supply resulted, at a certain point, in a qualitative change from compensatory to abnormal hypertrophy. The extent of left ventricular hypertrophy determined the severity of aortic stenosis and left ventricular dysfunction. The emergence of electrocardiographic signs of left ventricular hypertrophy and systolic overstrain is indicative of the defect acquiring a new quality--that of left ventricular and relative coronary insufficiency.
一项对61例先天性主动脉口狭窄患者的研究表明，左心室心肌功能障碍与心肌肥厚程度相关。左心室心肌肥厚不断发展与其血液供应之间的差异，在某一时刻导致了从代偿性肥厚到异常肥厚的质的变化。左心室肥厚的程度决定了主动脉狭窄和左心室功能障碍的严重程度。左心室肥厚和收缩期过度劳损的心电图征象的出现表明病变获得了一种新的性质——左心室和相对性冠状动脉供血不足的性质。
