Giroud M, Chirpaz L, Beuriat P, d'Athis P, Dusserre L, Binnert D, Dumas R
Presse Med. 1987 Jun 13;16(22):1079-82.
The short-term prognostic value of hyperglycemia in acute stroke has been evaluated from the results of the first year of activity of the Stroke Registration unit in Dijon. In 188 patients admitted to hospital for acute hemiplegia blood glucose levels were measured on admission and daily for 7 days thereafter, and a CT scan was performed within a fortnight. Mortality was significantly higher in hyperglycemic patients (more than 2 g of glucose per litre) than in normoglycemic patients. In hyperglycemic patients the increase in blood glucose level was correlated with the initial disturbances of consciousness, the severity of hemiplegia and the presence at CT of an haemorrhage or an infarct with oedematous reaction. Thus, hyperglycemia in acute stroke is related to the severity of the cerebral damage. As a factor of bad prognosis, it is as sensitive as disturbances of consciousness or severe brain lesions at CT.
第戎卒中登记部门开展活动的第一年结果对急性卒中患者高血糖的短期预后价值进行了评估。188例因急性偏瘫入院的患者在入院时及随后7天每天测量血糖水平,并在两周内进行CT扫描。高血糖患者(血糖超过每升2克)的死亡率显著高于血糖正常的患者。在高血糖患者中,血糖水平的升高与意识的初始障碍、偏瘫的严重程度以及CT显示的出血或伴有水肿反应的梗死灶相关。因此,急性卒中时的高血糖与脑损伤的严重程度有关。作为不良预后因素,它与意识障碍或CT显示的严重脑损伤一样敏感。