Dastiridou Anna, Chopra Vikas
Ophthalmology Department, University of Thessalia, Thessalia, Greece.
Doheny Image Reading Center, Doheny Eye Institute.
Curr Opin Ophthalmol. 2018 May;29(3):226-233. doi: 10.1097/ICU.0000000000000475.
Optical coherence tomography angiography (OCTA) is a novel, noninvasive imaging modality that allows assessment of the retinal and choroidal vasculature. The scope of this review is to summarize recent studies using OCTA in glaucoma and highlight potential applications of this new technology in the field of glaucoma.
OCTA studies have shown that retinal vascular changes may not develop solely as a result of advanced glaucoma damage. OCTA-derived measurements have provided evidence for lower retinal vascular densities at the optic nerve head, peripapillary and macula in preperimetric-glaucoma and early-glaucoma, as well as, in more advanced glaucoma, in comparison to with normal eyes.
OCTA is a novel imaging modality that has already started to expand our knowledge base regarding the role of ocular blood flow in glaucoma. Future studies will better elucidate the role of OCTA-derived measurements in clinical practice, research, and clinical trials in glaucoma.
光学相干断层扫描血管造影（OCTA）是一种新型的非侵入性成像方式，可用于评估视网膜和脉络膜血管系统。本综述的范围是总结近期在青光眼研究中使用OCTA的研究，并强调这项新技术在青光眼领域的潜在应用。
OCTA研究表明，视网膜血管变化可能并非仅由晚期青光眼损害所致。与正常眼睛相比，OCTA测量结果显示，在视野缺损前青光眼和早期青光眼中，视神经乳头、视乳头周围和黄斑处的视网膜血管密度较低，在更晚期青光眼中也是如此。
OCTA是一种新型成像方式，已经开始扩展我们关于眼血流在青光眼中作用的知识库。未来的研究将更好地阐明OCTA测量结果在青光眼临床实践、研究和临床试验中的作用。
