Shokoohi-Rad Saeed, Shoeibi Nasser, Ghasemi Nour Mohammad, Bakhtiari Elham
Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Student Research Committee, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.
Neuroophthalmology. 2021 Nov 4;46(3):147-153. doi: 10.1080/01658107.2021.1995442. eCollection 2022.
We conducted this study to assess the effect of religious fasting on intraocular pressure (IOP) as well as retinal parameters and retinal thickness during Ramadan using optical coherence tomography angiography (OCTA) performed on a spectral domain device. All the participants ate a pre-dawn meal and drink, and then fasted for at least 15 hours. We assessed a total of 61 eyes from 31 healthy volunteers with a mean age of 32.87 ± 8.07. A significant decrease was found in the median IOP after fasting at 10.00 mmHg in comparison with the pre-fasting value of 12.00 mmHg ( < .0001). Retinal peri-papillary capillary (RPC) whole image, RPC inside disk, and RPC mean values showed significant decreases after fasting ( = .011, .012, and .032 respectively). RPC whole vessel density (VD), RPC inside VD, and RPC VD mean values also showed significant decreases after fasting period ( = .025, <.0001, and .003, respectively). Religious fasting during the warm season could decrease IOP. It could also reduce the blood flow of the retina, specifically the macula, and the retinal peri-papillary VD.
我们开展这项研究，旨在通过使用光谱域设备进行光学相干断层扫描血管造影（OCTA），评估斋月期间宗教禁食对眼内压（IOP）以及视网膜参数和视网膜厚度的影响。所有参与者均在黎明前用餐和饮水，然后禁食至少15小时。我们评估了31名健康志愿者的61只眼睛，这些志愿者的平均年龄为32.87±8.07岁。与禁食前12.00 mmHg的眼压值相比，禁食后眼压中位数显著降低，为10.00 mmHg（<.0001）。视网膜视乳头周围毛细血管（RPC）的全图像、视盘内RPC以及RPC平均值在禁食后均显著降低（分别为.011、.012和.032）。禁食期后，RPC全血管密度（VD）、视盘内RPC的VD以及RPC的VD平均值也均显著降低（分别为.025、<.0001和.003）。温暖季节的宗教禁食可降低眼压。它还可能减少视网膜的血流，特别是黄斑区以及视网膜视乳头周围的血管密度。
