Tan Roy, Agrawal Rupesh, Taduru Swathi, Gupta Arushi, Vupparaboina Kiran, Chhablani Jay
Ophthalmic Surg Lasers Imaging Retina. 2018 Mar 1;49(3):191-197. doi: 10.3928/23258160-20180221-07.
To evaluate structural changes in the choroid of patients with retinitis pigmentosa (RP) using swept-source optical coherence tomography (OCT) scans.
A prospective study was conducted comparing 35 eyes of 35 patients with RP and 26 eyes of 26 normal patients. OCT images of the choroid were binarized into luminal and stromal areas to derive choroidal vascularity index (CVI). Subfoveal choroidal thickness (CT) was also measured and compared.
There was a significant decrease in the mean CVI among eyes with RP as compared to normal eyes (56.91 ± 1.43% vs. 59.47 ± 1.55%; P < .0001). Mean subfoveal CT was significantly greater in eyes with RP as compared to normal eyes (262.82 μm ± 69.69 μm vs. 194.65 μm ± 23.55 μm; P < .0001).
Patients with RP showed a significant reduction in CVI and an increase in CT as compared to normal eyes. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:191-197.].
采用扫频光学相干断层扫描（OCT）评估视网膜色素变性（RP）患者脉络膜的结构变化。
开展一项前瞻性研究，比较35例RP患者的35只眼与26例正常患者的26只眼。将脉络膜的OCT图像二值化为管腔和基质区域，以得出脉络膜血管指数（CVI）。还测量并比较了黄斑中心凹下脉络膜厚度（CT）。
与正常眼相比，RP患者眼中的平均CVI显著降低（56.91±1.43%对59.47±1.55%；P<.0001）。与正常眼相比，RP患者眼中的平均黄斑中心凹下CT显著更大（262.82μm±69.69μm对194.65μm±23.55μm；P<.0001）。
与正常眼相比，RP患者的CVI显著降低，CT增加。[《眼科手术、激光与视网膜成像》。2018年；49:191 - 197。]
