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微生物群与其宿主之间的协同作用:利用夏威夷群岛和当地合作网络解决微生物组研究中的紧迫问题。

Synergy among Microbiota and Their Hosts: Leveraging the Hawaiian Archipelago and Local Collaborative Networks To Address Pressing Questions in Microbiome Research.

作者信息

Hynson Nicole A, Frank Kiana L, Alegado Rosanna A, Amend Anthony S, Arif Mohammad, Bennett Gordon M, Jani Andrea J, Medeiros Matthew C I, Mileyko Yuriy, Nelson Craig E, Nguyen Nhu H, Nigro Olivia D, Prisic Sladjana, Shin Sangwoo, Takagi Daisuke, Wilson Samuel T, Yew Joanne Y

机构信息

Department of Botany, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA.

Pacific Biosciences Research Center, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA.

出版信息

mSystems. 2018 Mar 13;3(2). doi: 10.1128/mSystems.00159-17. eCollection 2018 Mar-Apr.

DOI:10.1128/mSystems.00159-17
PMID:29556540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5850080/
Abstract

Despite increasing acknowledgment that microorganisms underpin the healthy functioning of basically all multicellular life, few cross-disciplinary teams address the diversity and function of microbiota across organisms and ecosystems. Our newly formed consortium of junior faculty spanning fields such as ecology and geoscience to mathematics and molecular biology from the University of Hawai'i at Mānoa aims to fill this gap. We are united in our mutual interest in advancing a new paradigm for biology that incorporates our modern understanding of the importance of microorganisms. As our first concerted research effort, we will assess the diversity and function of microbes across an entire watershed on the island of Oahu, Hawai'i. Due to its high ecological diversity across tractable areas of land and sea, Hawai'i provides a model system for the study of complex microbial communities and the processes they mediate. Owing to our diverse expertise, we will leverage this study system to advance the field of biology.

摘要

尽管人们越来越认识到微生物是基本上所有多细胞生物健康运作的基础,但很少有跨学科团队研究不同生物和生态系统中微生物群的多样性和功能。我们新成立的由夏威夷大学马诺阿分校的初级教员组成的联盟,成员涵盖生态学、地球科学、数学和分子生物学等领域,旨在填补这一空白。我们因共同致力于推进一种新的生物学范式而团结在一起,这种范式融合了我们对微生物重要性的现代理解。作为我们的首次协同研究工作,我们将评估夏威夷瓦胡岛一个完整流域内微生物的多样性和功能。由于夏威夷在陆地和海洋的可研究区域具有高度的生态多样性,它为研究复杂的微生物群落及其介导的过程提供了一个模型系统。凭借我们多样的专业知识,我们将利用这个研究系统推动生物学领域的发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d749/5850080/768dd784443b/sys0021821840001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d749/5850080/768dd784443b/sys0021821840001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d749/5850080/768dd784443b/sys0021821840001.jpg

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本文引用的文献

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2
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PeerJ. 2017 Aug 28;5:e3730. doi: 10.7717/peerj.3730. eCollection 2017.
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Fungi associated with mesophotic macroalgae from the 'Au'au Channel, west Maui are differentiated by host and overlap terrestrial communities.
来自茂宜岛西部“奥奥海峡”的与中光层大型藻类相关的真菌因宿主而有所不同,且与陆地群落存在重叠。
PeerJ. 2017 Jul 11;5:e3532. doi: 10.7717/peerj.3532. eCollection 2017.
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Epidemic and endemic pathogen dynamics correspond to distinct host population microbiomes at a landscape scale.在景观尺度上,流行病和地方病病原体动态与不同的宿主种群微生物群落相对应。
Proc Biol Sci. 2017 Jun 28;284(1857). doi: 10.1098/rspb.2017.0944.
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Viruses in the Oceanic Basement.大洋底部的病毒。
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