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Hyperlipemic responses induced by centrally administered histamine H1- and H2-receptor agonists in rats.

作者信息

Bugajski J, Gadek A

出版信息

Agents Actions. 1987 Apr;20(3-4):255-7. doi: 10.1007/BF02074684.

DOI:10.1007/BF02074684
PMID:2955677
Abstract

The H1-receptor agonist 2-pyridylethylamine (PEA), and the H2-receptor agonists dimaprit and impromidine administered intracerebroventricularly (i.c.v.) to conscious rats considerably increased the concentration of free fatty acids (FFA) in the blood serum. The hyperlipemic effect of PEA was abolished by mepyramine, a H1-receptor antagonist. Responses to dimaprit and impromidine were not antagonized by cimetidine. These results suggest that central H1-receptor stimulation elicits the hyperlipemic responses in rats. The role of central H2-receptors in this reaction is not clear.

摘要

相似文献

1
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引用本文的文献

1
Dimaprit--induced neurotoxicity.二甲双胍诱导的神经毒性。 需注意，你原文中的“Dimaprit”可能有误，常见的是“Dimethylbiguanide”（二甲双胍），如果是准确的词汇，请告知我以便更准确翻译。 按照你给定的原文翻译如上。
Agents Actions. 1992 Mar;35(3-4):179-84. doi: 10.1007/BF01997497.

本文引用的文献

1
ADVENTITIOUS FACTORS AFFECTING THE CONCENTRATON OF FREE FATTY ACIDS IN THE PLASMA OF RATS.影响大鼠血浆中游离脂肪酸浓度的外来因素
Br J Pharmacol Chemother. 1964 Jun;22(3):577-84. doi: 10.1111/j.1476-5381.1964.tb01711.x.
2
Impromidine, a potent inhibitor of histamine methyltransferase (HMT) and diamine oxidase (DAO).英普咪定，一种组胺甲基转移酶（HMT）和二胺氧化酶（DAO）的强效抑制剂。
Biochem Pharmacol. 1980 Oct 15;29(20):2897-900. doi: 10.1016/0006-2952(80)90033-7.
3
Central histaminergic stimulation of pituitary--adrenocortical response in the rat.
大鼠垂体-肾上腺皮质反应的中枢组胺能刺激
Life Sci. 1983 Sep 19;33(12):1179-89. doi: 10.1016/0024-3205(83)90023-1.
4
Evidence for and against heterogeneity in the histamine H2-receptor population.支持和反对组胺H2受体群体异质性的证据。
Pharmacology. 1981;23(1):1-13. doi: 10.1159/000137522.
5
Lipolytic responses induced by intracerebroventricular administration of histamine in the rat.大鼠脑室内注射组胺诱导的脂解反应。
Agents Actions. 1981 Apr;11(1-2):147-50. doi: 10.1007/BF01991485.
6
Central histaminergic stimulation of hyperlipemic response in rats under stress.
Agents Actions. 1985 Apr;16(3-4):236-9. doi: 10.1007/BF01983149.
7
Dimaprit -(S-[3-(N,N-dimethylamino)prophyl]isothiourea) - a highly specific histamine H2 -receptor agonist. Part 1. Pharmacology.二甲双胍 -（S-[3-(N,N-二甲基氨基)丙基]异硫脲）- 一种高度特异性的组胺H2受体激动剂。第一部分。药理学。
Agents Actions. 1977 Mar;7(1):31-7. doi: 10.1007/BF01964878.
8
Impromidine (SK&F 92676) is a very potent and specific agonist for histamine H2 receptors.英普咪定（SK&F 92676）是一种效力很强且特异性很高的组胺H2受体激动剂。
Nature. 1978 Nov 23;276(5686):403-5. doi: 10.1038/276403a0.
9
Effect of intraventricular histamine on hormone secretion in dogs.脑室内组胺对犬类激素分泌的影响。
Neuroendocrinology. 1979;29(3):169-77. doi: 10.1159/000122919.