Li Kun, Luo Houqiang, Shahzad Muhammad
College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, People's Republic of China.
College of Animal Sciences, Wenzhou Vocational College of Science and Technology, Wenzhou, 325006, People's Republic of China.
Trop Anim Health Prod. 2018 Aug;50(6):1395-1398. doi: 10.1007/s11250-018-1561-3. Epub 2018 Mar 20.
Coxiella burnetii (C. burnetii) is an intracellular bacterium, which causes zoonotic disease called Q-fever. However, scarce information is known about the epidemiology of Q-fever in goats in Hubei province of China. A total of 1157 blood samples were collected from the study area and these were tested for antibodies against C. burnetii by employing a commercial competitive ELISA. The results showed that the overall positive rate of C. burnetii was 4.75% (95% CI: 3.6, 6.1) and in different counties it ranged from 1.05 to 11.84% in goats. Antibodies positive against C. burnetii were detected in 24 (4.68%; 95% CI: 3.0, 6.9) out of 513 male goats and 31 (4.81; 95% CI: 3.3, 6.8) out of 644 female goats. In different seasons, the seroprevalence of C. burnetii infection in goats was 6.81% (95% CI: 3.9, 10.8) in spring, 5.46% (95% CI: 3.4, 8.3) in summer, 4.73% (95% CI: 2.1, 9.1) in autumn, and 2.84% (95% CI: 1.4, 5.0) in winter. The present survey reveals that C. burnetii is prevalent in goats in Hubei province. Considering the numerous economic losses and potential risk to public health due to Q-fever, it is important that control measures should be adopted to prevent the transmission of this intracellular bacterium in animals and humans in Hubei province.
伯氏考克斯氏体（C. burnetii）是一种胞内细菌，可引发人畜共患病——Q热。然而，关于中国湖北省山羊Q热的流行病学情况，人们所知甚少。从研究区域共采集了1157份血样，并采用商业竞争ELISA法检测了针对伯氏考克斯氏体的抗体。结果显示，伯氏考克斯氏体的总体阳性率为4.75%（95%置信区间：3.6，6.1），在不同县份的山羊中，其阳性率在1.05%至11.84%之间。在513只雄性山羊中，检测到24只（4.68%；95%置信区间：3.0，6.9）针对伯氏考克斯氏体的抗体呈阳性；在644只雌性山羊中，检测到31只（4.81%；95%置信区间：3.3，6.8）抗体呈阳性。在不同季节，山羊中伯氏考克斯氏体感染的血清阳性率在春季为6.81%（95%置信区间：3.9，10.8），夏季为5.46%（95%置信区间：3.4，8.3），秋季为4.73%（95%置信区间：2.1，9.1），冬季为2.84%（95%置信区间：1.4，5.0）。本次调查表明，伯氏考克斯氏体在湖北省山羊中普遍存在。鉴于Q热会造成大量经济损失并对公众健康构成潜在风险，采取控制措施以防止这种胞内细菌在湖北省动物和人类中传播非常重要。
