van der Baan S, Veerman A J, Bezemer P D, Feenstra L
Ann Otol Rhinol Laryngol. 1987 May-Jun;96(3 Pt 1):264-72. doi: 10.1177/000348948709600306.
In this study the ultrastructure of cilia in patients with primary ciliary dyskinesia was compared to that in patients with other respiratory infections and with that in healthy individuals. After statistical analysis of the findings, the prevalence and the specificity of morphological changes in primary ciliary dyskinesia were established. Guidelines were developed by which the existence of primary ciliary dyskinesia can be ascertained in biopsies of nasal mucosa via transmission electron microscopy.
在本研究中，将原发性纤毛运动障碍患者的纤毛超微结构与其他呼吸道感染患者以及健康个体的纤毛超微结构进行了比较。对研究结果进行统计分析后，确定了原发性纤毛运动障碍形态学改变的患病率和特异性。制定了指导方针，通过透射电子显微镜检查可在鼻黏膜活检中确定原发性纤毛运动障碍的存在。
