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从用二极管灯和卤素灯聚合的复合牙科材料中释放的TEGDMA和UDMA单体。

TEGDMA and UDMA monomers released from composite dental material polymerized with diode and halogen lamps.

作者信息

Wacławczyk Agnieszka, Postek-Stefańska Lidia, Pietraszewska Daria, Birkner Ewa, Zalejska-Fiolka Jolanta, Wysoczańska-Jankowicz Iwona

机构信息

Department of Pediatric Dentistry, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Poland.

Department of Biochemistry, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia in Katowice, Poland.

出版信息

Adv Clin Exp Med. 2018 Apr;27(4):469-476. doi: 10.17219/acem/68382.

Abstract

BACKGROUND

More than 35 substances released from composite fillings have been identified. Among these, basic monomers and the so-called co-monomers are most often reported. The substances released from polymer-based materials demonstrate allergenic, cytotoxic, genotoxic, mutagenic, embryotoxic, teratogenic, and estrogenic properties.

OBJECTIVES

The aim of this study was to measure the amounts of triethylene glycol dimethacrylate (TEGDMA) and urethane dimethacrylate (UDMA) monomers released from composite dental fillings to citrate-phosphate buffer with the pH of 4, 6, 8 after 24 h and 6 months from the polymerization.

MATERIAL AND METHODS

Ten samples for each polymerization method had been made from the composite material (Filtek Supreme XT, 3M ESPE, St. Paul, USA), which underwent polymerization using the following lamps: halogen lamp (Translux CL, Heraeus Kulzer, Hanau, Germany) (sample H) and diode lamp (Elipar Freelight 2, 3M ESPE), with soft start function (group DS) and without that function (group DWS).

RESULTS

It has been demonstrated that the type of light-curing units has a significant impact on the amount of TEGDMA and UDMA released. The amount of UDMA and TEGDMA monomers released from composite fillings differed significantly depending on the source of polymerization applied, as well as the pH of the solution and sample storage time.

CONCLUSIONS

Elution of the monomers from composite material polymerized using halogen lamp was significantly greater as compared to curing with diode lamps.

摘要

背景

已鉴定出从复合填充物中释放的35种以上物质。其中,基本单体和所谓的共聚单体最常被报道。从聚合物基材料中释放的物质具有致敏、细胞毒性、遗传毒性、诱变、胚胎毒性、致畸和雌激素特性。

目的

本研究的目的是测量复合牙科填充物在聚合后24小时和6个月时释放到pH值为4、6、8的柠檬酸-磷酸盐缓冲液中的二甲基丙烯酸三乙二醇酯(TEGDMA)和二甲基丙烯酸聚氨酯(UDMA)单体的量。

材料与方法

用复合材料(Filtek Supreme XT,3M ESPE,美国圣保罗)制作每种聚合方法的10个样本,使用以下灯进行聚合:卤素灯(Translux CL,贺利氏古莎,德国哈瑙)(样本H)和二极管灯(Elipar Freelight 2,3M ESPE),有软启动功能(DS组)和无该功能(DWS组)。

结果

已证明光固化单元的类型对TEGDMA和UDMA的释放量有显著影响。从复合填充物中释放的UDMA和TEGDMA单体的量因应用的聚合源、溶液的pH值和样品储存时间而有显著差异。

结论

与用二极管灯固化相比,用卤素灯聚合的复合材料中单体的洗脱量明显更大。

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