Shafer R, Shafer N, Positano R G
Clin Podiatr Med Surg. 1987 Jul;4(3):729-42.
The time has long since passed when gangrene followed by amputation was the anticipated outcome of peripheral vascular disease of the extremities. Nevertheless, today in the United States it is estimated that there are more than half a million amputees. With preventive measures, early diagnosis, and adequate treatment, gangrene will be avoided and the patient will retain the use of his limbs.