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早期大剂量静脉注射维生素 C 在缺血/再灌注损伤中的意义。

Making sense of early high-dose intravenous vitamin C in ischemia/reperfusion injury.

机构信息

VU University Medical Center Amsterdam, Department of Intensive Care Medicine, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.

出版信息

Crit Care. 2018 Mar 20;22(1):70. doi: 10.1186/s13054-018-1996-y.

DOI:10.1186/s13054-018-1996-y
PMID:29558975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5861638/
Abstract

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2018. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2018 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901 .

摘要

本文选自《2018 年重症监护和急诊医学年度更新》的十篇综述之一。其他精选文章可在 https://www.biomedcentral.com/collections/annualupdate2018 在线查阅。有关《重症监护和急诊医学年度更新》的更多信息,请访问 http://www.springer.com/series/8901。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/f71596867024/13054_2018_1996_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/2bd58e07a9e5/13054_2018_1996_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/86610fcae9f5/13054_2018_1996_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/15b5cb5c53d0/13054_2018_1996_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/f71596867024/13054_2018_1996_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/2bd58e07a9e5/13054_2018_1996_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/86610fcae9f5/13054_2018_1996_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/15b5cb5c53d0/13054_2018_1996_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14fc/5861638/f71596867024/13054_2018_1996_Fig4_HTML.jpg

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Int J Surg. 2017 Jan;37:58-64. doi: 10.1016/j.ijsu.2016.12.009. Epub 2016 Dec 9.
2
Hydrocortisone, Vitamin C, and Thiamine for the Treatment of Severe Sepsis and Septic Shock: A Retrospective Before-After Study.氢化可的松、维生素C和硫胺素治疗严重脓毒症和脓毒性休克:一项前后对照的回顾性研究。
Chest. 2017 Jun;151(6):1229-1238. doi: 10.1016/j.chest.2016.11.036. Epub 2016 Dec 6.
3
坏死性软组织感染患者的营养支持:从重症监护病房到门诊护理
J Clin Med. 2025 May 3;14(9):3167. doi: 10.3390/jcm14093167.
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Steroid, thiamine, and ascorbic acid during post-resuscitation period for comatose out-of-hospital cardiac arrest survivors (STAR) trial: Protocol for a clinical trial.院外心脏骤停昏迷幸存者复苏后阶段使用类固醇、硫胺素和抗坏血酸(STAR)试验:一项临床试验方案
PLoS One. 2025 Apr 11;20(4):e0319733. doi: 10.1371/journal.pone.0319733. eCollection 2025.
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