McCrimmon Tara, Witte Susan, Mergenova Gaukhar, Terlikbayeva Assel, Primbetova Sholpan, Kuskulov Azamat, Bellamy Scarlett L, El-Bassel Nabila
Global Health Research Center of Central Asia, Almaty, Kazakhstan.
Columbia University of Social Work, 1255 Amsterdam Ave, New York, NY, 10027, USA.
Trials. 2018 Mar 20;19(1):187. doi: 10.1186/s13063-018-2566-y.
Among women at high risk for HIV and other sexually transmitted diseases (STIs), gender and economic issues limit the impact of behavioral prevention strategies. Women in Kazakhstan with dual risks of sex trading and drug use face elevated risk for HIV and STIs and may benefit from an economic empowerment intervention which combines HIV-risk reduction (HIVRR) education with financial skills-building and asset-building to promote reduced reliance on sex trading for income.
METHODS/DESIGN: The study employs a two-arm, cluster-randomized controlled trial (c-RCT) design. We will use cluster randomization to assign 350 women in approximately 50 cohorts to a traditional four-session HIV-risk-reduction intervention combined with a six-session financial literacy intervention, enrollment in a 24-session vocational training program and receipt of matched savings (HIVRR+MF); or to the four-session HIV-risk-reduction intervention alone (HIVRR). Repeated behavioral and biological assessments will be conducted at baseline, then at 6, 9, and 15 months post randomization/session 1.
This study responds to an identified need in the academic literature for rigorous testing of structural interventions, including combination microfinance and HIV-prevention interventions.
ClinicalTrials.gov, ID: NCT02406482 . Registered on 30 March 2015.
在感染艾滋病毒和其他性传播感染（STIs）风险较高的女性中，性别和经济问题限制了行为预防策略的效果。哈萨克斯坦从事性交易和吸毒双重风险行为的女性面临着更高的艾滋病毒和性传播感染风险，她们可能会从一项经济赋权干预措施中受益，该措施将降低艾滋病毒风险（HIVRR）教育与金融技能培养和资产建设相结合，以促进减少对性交易收入的依赖。
方法/设计：本研究采用双臂、整群随机对照试验（c-RCT）设计。我们将使用整群随机化方法，将约50个群组中的350名女性分配到以下两组：一组接受传统的为期四节的降低艾滋病毒风险干预措施，并结合为期六节的金融知识干预措施，参加为期24节的职业培训课程并获得匹配储蓄（HIVRR+MF）；另一组仅接受为期四节的降低艾滋病毒风险干预措施（HIVRR）。在基线时进行重复的行为和生物学评估，然后在随机分组/第1节之后的6、9和15个月进行评估。
本研究回应了学术文献中对包括小额融资与艾滋病毒预防相结合的结构性干预措施进行严格测试的明确需求。
ClinicalTrials.gov，标识符：NCT02406482。于2015年3月30日注册。
