Waxman K, Formosa P, Soliman H, Tominaga G, Police A, Hyatt J
Crit Care Med. 1987 Aug;15(8):780-3. doi: 10.1097/00003246-198708000-00015.
Cutaneous blood flow may be an indirect measure of circulatory function estimated by continuous, noninvasive laser Doppler velocimetry (LDV). It has been postulated that LDV may be a useful monitor of cardiac output changes. To test this hypothesis, LDV was evaluated in 67 critically ill adult patients with simultaneous measurements of cardiac index (CI) and other physiologic variables. Heated and unheated laser probes were utilized. The results indicate that LDV reflects acute directional changes of CI. Further, with the heated laser probe, the magnitude of acute CI change is reflected. However, there are gradual changes over time of LDV which may occur independently of CI or other monitored variables. Hence, absolute LDV values are not predictive of absolute CI values.
皮肤血流可能是通过连续、无创激光多普勒测速仪(LDV)估计的循环功能的间接指标。据推测,LDV可能是心输出量变化的有用监测指标。为了验证这一假设,对67例危重症成年患者进行了LDV评估,同时测量心指数(CI)和其他生理变量。使用了加热和未加热的激光探头。结果表明,LDV反映了CI的急性方向变化。此外,使用加热的激光探头时,CI急性变化的幅度也能得到反映。然而,LDV会随时间发生逐渐变化,这种变化可能独立于心指数或其他监测变量而出现。因此,LDV的绝对值并不能预测CI的绝对值。