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原发性颈神经母细胞瘤:一例报告。

Primary cervical ganglioneuroblastoma: A case report.

作者信息

Lu Dan, Liu Jun, Chen Yuan, Chen Fei, Yang Hui

机构信息

Department of Otorhinolaryngology, Head & Neck Surgery, West China Hospital.

West China School of Stomatology, Sichuan University, Sichuan, China.

出版信息

Medicine (Baltimore). 2018 Mar;97(12):e0090. doi: 10.1097/MD.0000000000010090.

Abstract

RATIONALE

Ganglioneuroblastoma is usually located in the adrenal gland, retroperitoneal ganglia, or posterior mediastinum, but rarely occurs in the parapharyngeal space.

PATIENT CONCERNS

A 4-year-old girl presented with complaint of progressive inspiratory dyspnea and dysphagia, accompanying left-side Horner's syndrome.

DIAGNOSE

Computed tomography (CT) scan revealed a giant mass with irregular low density in left oropharyngeal and posterior pharyngeal wall. The left carotid artery sheath was pushed to the right. After enhancement, the central part of the mass was strengthened, and the surrounding bones structures appeard normal. Magnetic resonance imaging (MRI) showed a solid mass in the left parapharyngeal space displacing the left carotid sheath posteriorly and laterally. A ganglioneuroblastoma was diagnosed.

INTERVATIONS

The girl was treated by surgery.

OUTCOMES

The postoperative course was uneventful. There was no recurrence was observed during the 1-year follow-up.

LESSONS

The primary cervical ganglioneuroblastoma is rare, we recommended the ganglioneuroblastoma should be considered in the differential diagnosis of a child presenting with a parapharyngeal space mass.

摘要

理论依据

神经节神经母细胞瘤通常位于肾上腺、腹膜后神经节或后纵隔,但很少发生于咽旁间隙。

患者情况

一名4岁女孩因进行性吸气性呼吸困难和吞咽困难就诊,并伴有左侧霍纳综合征。

诊断

计算机断层扫描(CT)显示左侧口咽和咽后壁有一个巨大的不规则低密度肿块。左侧颈动脉鞘被推向右方。增强后,肿块中央部分强化,周围骨骼结构正常。磁共振成像(MRI)显示左侧咽旁间隙有一个实性肿块,将左侧颈动脉鞘向后外侧推移。诊断为神经节神经母细胞瘤。

干预措施

该女孩接受了手术治疗。

结果

术后过程顺利。在1年的随访中未观察到复发。

经验教训

原发性颈部神经节神经母细胞瘤罕见,对于出现咽旁间隙肿块的儿童,我们建议在鉴别诊断中考虑神经节神经母细胞瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2a1/5895351/73259d336f4d/medi-97-e0090-g001.jpg

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