甜蜜的线粒体：阿尔茨海默病的捷径。
Sweet Mitochondria: A Shortcut to Alzheimer's Disease.
机构信息
CNC - Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
出版信息
J Alzheimers Dis. 2018;62(3):1391-1401. doi: 10.3233/JAD-170931.
Abstract
A growing body of evidence supports a clear association between Alzheimer's disease and diabetes and several mechanistic links have been revealed. This paper is mainly devoted to the discussion of the role of diabetes-associated mitochondrial defects in the pathogenesis of Alzheimer's disease. The research experience and views of the author on this subject will be highlighted.
摘要
越来越多的证据支持阿尔茨海默病与糖尿病之间存在明确的关联，并且已经揭示了几种机制联系。本文主要致力于讨论与糖尿病相关的线粒体缺陷在阿尔茨海默病发病机制中的作用。本文将重点介绍作者在这一主题上的研究经验和观点。
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